ABC of monitoring drug therapy. Measuring plasma drug concentrations.

JK Aronson, M Hardman - BMJ: British Medical Journal, 1992 - ncbi.nlm.nih.gov
… Formulation-Some drugs-for example, digoxin-are better absorbed … Drug interactions-Forexample,
quinidine and verapamil … criteria above interpretation ofthe plasma drug Amiodarone

Clinical use of serum digoxin concentrations

RP Lewis - The American journal of cardiology, 1992 - Elsevier
Digoxin is not bound by adipose tissue, so the dose should be based on lean body mass .31
Amiodarone may affect digoxin’… by their direct effects on the kidney.33,34 Quinidine inhibits …

Mitochondrial toxicity of cardiac drugs and its relevance to mitochondrial disorders

J Finsterer, S Zarrouk-Mahjoub - Expert Opinion on Drug …, 2015 - Taylor & Francis
should be applied with particular caution in patients with MIDs include amiodarone, phenytoin,
lidocaine, quinidine, … autophagy (verapamil), calcium overload of mitochondria (digitalis), …

Antibodies and digitalis: The modern revolution in the use of an ancient drug

E Haber - Journal of the American College of Cardiology, 1985 - Elsevier
digoxin concentration can occur after quinidine administration which … It is of interest that
toxic effects as a result of a verapamil-… After 3 to 7 days of amiodarone treatment. the plasma …

Drug prescribing for elderly patients

DS Chutka, JM Evans, KC Fleming… - Mayo Clinic …, 1995 - Elsevier
… The potential for digoxin toxicity may be enhanced when drugs such as verapamil
hydrochloride, amiodarone, or quinidine are used concomitantly. The Vd for digoxin is reduced in …

Renal targeted therapies of antihypertensive and cardiovascular drugs for patients with stages 3 through 5d kidney disease

O Ai Dhaybi, GL Bakris - Clinical Pharmacology & Therapeutics, 2017 - Wiley Online Library
… by 50% when amiodarone is started, and the plasma digoxin level should be monitored closely.
… , spironolactone, quinidine, and verapamil. Quinidine and propafenone displace digoxin

The interaction of mexiletine with other cardiovascular drugs

JT Bigger Jr - American Heart Journal, 1984 - Elsevier
… been found that quinidine can displace digoxin from tissue … a single agent was effective when
combined with amiodarone. … effect of verapamil on plasma digoxin concentration and renal …

[PDF][PDF] Colchicine for cardiovascular therapy: A drug interaction perspective and a safety meta-analysis

S Şen, E Karahan, C Büyükulaş… - Anatolian Journal of …, 2021 - jag.journalagent.com
… The most commonly used lipid lowering treatments including all statins and fibrates but not
blockers including verapamil and diltiazem; and amiodarone, digoxin, and quinidine have seri…

[PDF][PDF] Drug interactions-mechanisms and clinical implications

HM Lal, U Lal - Medicine update, 2008 - Citeseer
… include digoxin with quinidine, rifampicin or verapamil; and … Digoxin is not extensively
metabolized but it is transported by … like quinidine, verapamil and amiodarone, leading to digoxin

Digoxin: its role in contemporary medicine

MA Stucky, ZD Goldberger - Postgraduate medical journal, 2015 - academic.oup.com
verapamil) slow digoxin metabolism. Quinidine (less commonly used now) and amiodarone
also significantly increase digoxin concentrations, requiring digoxin dosing to be decreased …