Male germ cell development in humans

JB Stukenborg, KR Kjartansdóttir, A Reda… - Hormone research in …, 2014 - karger.com
… , differentiation and apoptosis of human male germ cells still … male germ cells related to
dysfunctional spermatogenesis. … steroidogenic function and results in a spermatogenic arrest at …

Global changes in epigenomes during mouse spermatogenesis: possible relation to germ cell apoptosis

T Koji, Y Shibata - Histochemistry and Cell Biology, 2020 - Springer
… into spermatogonia and then they enter the first wave of … be necessary for the complete
understanding of the bona fide function of the epigenomes in mammalian spermatogenesis. …

Apoptosis and blood–testis barrier during the first spermatogenic wave in the pubertal rat

A Morales, F Mohamed… - … in Integrative Anatomy and …, 2007 - Wiley Online Library
… (1997), the massive wave of germ cell apoptosis seems to be necessary for normal mature …
structure and function of pachytene apoptosis in the first wave of spermatogenesis is needed. …

The Fas System, a Regulator of Testicular Germ Cell Apoptosis, Is Differentially Up-Regulated in Sertoli Cell Versus Germ Cell Injury of the Testis

J Lee, JH Richburg, EB Shipp, ML Meistrich… - …, 1999 - academic.oup.com
… and a decreased incidence of germ cell apoptosis (12, 13). Targeted … of spermatogonia as
well as massive death of early … the function of the Sertoli cell. The identification of the target …

Programmed cell death in the germline

JS Baum, JPS George, K McCall - Seminars in Cell & Developmental …, 2005 - Elsevier
… to function as early extracellular signals for the induction of … the first few weeks of postnatal
life, an early large wave of … levels of germ cell apoptosis are seen in spermatogonia and …

Role of Sertoli cells in injury‐associated testicular germ cell apoptosis

K Boekelheide, SL Fleming, KJ Johnson… - Proceedings of the …, 2000 - Wiley Online Library
… of the Sertoli-germ cell interaction during testicular injury, we will first review the … function
of the pro-survival SCF/c-kit system and the pro-apoptotic FasL/Fas system in spermatogenesis, …

Spermatogenesis and germ cell death

APS Hikim, YH Lue, C Wang, RS Swerdloff - Male Reproductive Function, 1999 - Springer
… the role of programmed gem cell death in spermatogenesis, as well as … early and massive
wave of germinal cell apoptosis is required for the development of functional spermatogenesis

Establishment of oocyte population in the fetal ovary: primordial germ cell proliferation and oocyte programmed cell death

M De Felici, FG Klinger, D Farini, ML Scaldaferri… - Reproductive …, 2005 - Elsevier
… by a first phase occurring during embryo–fetal life and in common with spermatogenesis, …
The larger and more rapid wave of oocyte degeneration occurs in the pre-follicular stage …

Stem cell factor protects germ cells from apoptosis in vitro

W Yan, J Suominen, J Toppari - Journal of cell science, 2000 - journals.biologists.com
… In the present study, the number of apoptotic spermatocytes and … early and massive
wave of germinal cell apoptosis is required for the development of functional spermatogenesis

Redistribution of Bax is an early step in an apoptotic pathway leading to germ cell death in rats, triggered by mild testicular hyperthermia

CM Yamamoto, AP Sinha Hikim, PN Huynh… - Biology of …, 2000 - academic.oup.com
early germ cells is balanced by selective apoptosis [1–3]. In the adult rat, A 2–4 spermatogonia
and spermatocytes … -2 proteins have been implicated to function as membrane pores or …