Efficacy, safety, and durability of repeated ketamine infusions for comorbid posttraumatic stress disorder and treatment-resistant depression

CS Albott, KO Lim, MK Forbes, C Erbes… - The Journal of clinical …, 2018 - psychiatrist.com
major depressive disorder (N = 15) received 6 intravenous … interest in the rapid antidepressant
effects of ketamine—an N-… randomized controlled trials of single infusions of ketamine

… effectiveness of repeated intravenous ketamine on subjective and objective psychosocial function in patients with treatment-resistant depression and suicidal ideation

Y Zhou, C Wang, X Lan, W Zheng, H Li, Z Chao… - Journal of Affective …, 2022 - Elsevier
Ketamine has rapid and robust antidepressant effects in … ); moderate to severe depressive
symptom severity assessed by … for prioritizing larger randomized controlled studies evaluating …

Ketamine augmentation for major depressive disorder and suicidal ideation: preliminary experience in an inpatient psychiatry setting

M Sinyor, M Williams, S Belo, B Orser, M Vincent… - Journal of affective …, 2018 - Elsevier
randomized controlled trials to confirm the efficacy of serial … suffering from treatment-resistant
major depressive disorder (… (defined as ≥ 2 failed lifetime antidepressant trials of adequate …

… predict antidepressant effects 24 hours after infusion of racemic ketamine and esketamine in treatment-resistant depression? A secondary analysis from a randomized …

AT Caliman-Fontes, M Telles… - … in Psychiatry and …, 2023 - trends.periodikos.com.br
Major depressive disorder (MDD) is a recurrent … study with 108 patients diagnosed with
TRD or bipolar disorder, to evaluate possible predictors of antidepressant efficacy after ketamine

Efficacy of single and repeated administration of ketamine in unipolar and bipolar depression: a meta-analysis of randomized clinical trials

J Kryst, P Kawalec, AM Mitoraj, A Pilc, W Lasoń… - Pharmacological …, 2020 - Springer
… published peer-reviewed randomized controlled trials (RCTs) … for major depression (unipolar
or bipolar, treatment-resistant or … modest antidepressant efficacy of repeated oral ketamine; …

Study protocol for Ketamine as an adjunctive therapy for major depression (2): a randomised controlled trial (KARMA-Dep [2])

A Jelovac, C McCaffrey, M Terao, E Shanahan… - BMC psychiatry, 2023 - Springer
… strategy for increasing ketamine’s antidepressant efficacy and/or … on the efficacy and safety
of repeated ketamine infusions against … ketamine in treatment-resistant depression: a pilot …

Ketamine for the treatment of major depression: a systematic review and meta-analysis

S Nikolin, A Rodgers, A Schwaab, A Bahji… - …, 2023 - thelancet.com
… CENTRAL up to April 13, 2023, for randomised controlled trials (RCTs) investigating ketamine
for … contributing to the antidepressant efficacy of ketamine. Therefore, clinics and research …

Randomized trial of ketamine masked by surgical anesthesia in patients with depression

TR Lii, AE Smith, JR Flohr, RL Okada… - Nature Mental …, 2023 - nature.com
… assessing the antidepressant efficacy of intravenous ketamine … those with treatment-resistant
depression (TRD) 3,4,5 . Across … In most randomized controlled trials (RCTs) of ketamine for …

The potential pro-cognitive effects with intravenous subanesthetic ketamine in adults with treatment-resistant major depressive or bipolar disorders and suicidality

Y Zhou, C Wang, X Lan, W Zheng, H Li, Z Chao… - Journal of Psychiatric …, 2021 - Elsevier
Ketamine has rapid and robust antidepressant effects in depression, while its effects on
cognitive … This aim of the study herein is to determine whether ketamine has direct pro-cognitive …

Efficacy of esketamine nasal spray plus oral antidepressant treatment for relapse prevention in patients with treatment-resistant depression: a randomized clinical trial

EJ Daly, MH Trivedi, A Janik, H Li, Y Zhang, X Li… - JAMA …, 2019 - jamanetwork.com
… Patients with treatment-resistant major depressive disorder (… -term antidepressant effects
of esketamine and ketamine, 13 ,… double-blind, active-controlled studies (1 fixed dose and 1 …