Safety, tolerability, and real-world effectiveness of intravenous ketamine in older adults with treatment-resistant depression: a case series

O Lipsitz, JD Di Vincenzo, NB Rodrigues… - The American Journal of …, 2021 - Elsevier
Major depressive disorder (MDD) is a prevalent psychiatric … 18–65), however randomized
controlled trials (RCTs) in older … sustained antidepressant effect following repeated IV ketamine

Ketamine in the treatment of depressive episodes

P Ritter, H Findeis, M Bauer - Pharmacopsychiatry, 2020 - thieme-connect.com
randomized controlled trial in the year 2000, numerous studies have explored the antidepressant
efficacy … , treatment-resistant depression, and bipolar depression both as single agent …

Rapid and longer-term antidepressant effects of repeated-dose intravenous ketamine for patients with unipolar and bipolar depression

W Zheng, YL Zhou, WJ Liu, CY Wang, YN Zhan… - Journal of psychiatric …, 2018 - Elsevier
Ketamine has shown antidepressant efficacy within hours of … safe and efficacious for ten
patients with treatment-resistant … meta-analysis including 50 randomized controlled trials (RCTs) (…

[HTML][HTML] The efficacy and safety of esketamine in the treatment of major depressive disorder with suicidal ideation: study protocol for a randomized controlled trial

H Liu, X Lan, C Wang, F Zhang, L Fu, W Li, Y Ye, Z Hu… - BMC psychiatry, 2022 - Springer
… Previous ketamine-related trials have mostly focused on adults but lack evidences from …
trials and one randomized controlled trial have reported antidepressant efficacy of ketamine in …

[HTML][HTML] … integrative approach to ketamine therapy may enhance multiple dimensions of efficacy: improving therapeutic outcomes with treatment resistant depression

SA Muscat, G Hartelius, CR Crouch… - Frontiers in Psychiatry, 2021 - frontiersin.org
… of treatment resistant major depressive disorder received one … of the antidepressant
effectiveness of ketamine. This theory … studies, of which 60 were included: 20 randomized control

[HTML][HTML] Ketamine and Other Glutamate Receptor Modulating Agents for Treatment-Resistant Depression: A Systematic Review of Randomized Controlled Trials

A Shamabadi, A Ahmadzade, A Aqamolaei… - Iranian Journal of …, 2022 - ncbi.nlm.nih.gov
… refers to major depressive episodes that do not respond satisfactorily to at least two trials of
antidepressant … In this article, we reviewed the antidepressant efficacy and safety of different …

[HTML][HTML] A higher dose (0.8 mg/kg) of ketamine infusion for treatment-resistant depression: An open-label study in Taiwan

MH Chen, WC Lin, CT Li, TP Su - Taiwanese Journal of …, 2020 - journals.lww.com
… ) of ketamine infusion has a higher antidepressant efficacy and … DSM-IV criteria for major
depressive disorder, recurrent without … , double-blind, placebo-control trial to validate the results. …

Maintaining rapid antidepressant effects following ketamine infusion: a major unmet need

GI Papakostas - The Journal of Clinical Psychiatry, 2020 - psychiatrist.com
… of intranasal esketamine for treatment-resistant depression—a … gains of intravenous ketamine
for major depressive disorder. A … To date, several randomized controlled trials8-13 have …

The potential pro-cognitive effects with intravenous subanesthetic ketamine in adults with treatment-resistant major depressive or bipolar disorders and suicidality

Y Zhou, C Wang, X Lan, W Zheng, H Li, Z Chao… - Journal of Psychiatric …, 2021 - Elsevier
Ketamine has rapid and robust antidepressant effects in depression, while its effects on
cognitive … This aim of the study herein is to determine whether ketamine has direct pro-cognitive …

Ketamine Therapy for Treatment-Resistant Depression

LA McInnes, M Ettensohn - … in Psychedelic Medicine: State-of-the-Art …, 2019 - torrossa.com
Antidepressant efficacy of ketamine in treatment-resistant major depression: A two-site
randomized controlled trial… repeated ketamine infusions in treatment-resistant major depression. …