Host cells: mobilizable lipid resources for the intracellular parasite Toxoplasma gondii

AJ Charron, LD Sibley - Journal of cell science, 2002 - journals.biologists.com
… that parasites readily scavenged long-chain fatty acids as well … cell organelles, which may
facilitate the intracellular survival … When apicoplast DNA was visualized using the nucleic acid

Heterologous expression, purification, and partial characterisation of the apicoplast protein 3-oxoacyl-[acyl-carrier-protein] reductase from Toxoplasma gondii

C Aygün, S Kocer, Ö Danış, S Cubuk, O Mutlu - Protein Expression and …, 2023 - Elsevier
… In summary, TgFabG, an essential enzyme of a vital fatty acid synthesis pathway in the
apicomplexan parasite Toxoplasma gondii, was recombinantly produced, over-expressed, …

[HTML][HTML] Differential contribution of two organelles of endosymbiotic origin to iron-sulfur cluster synthesis and overall fitness in Toxoplasma

S Pamukcu, A Cerutti, Y Bordat, S Hem… - PLoS …, 2021 - journals.plos.org
… fitness of Toxoplasma gondii, an apicomplexan parasite causing … for the synthesis of isoprenoid
precursors, a type II fatty acid … We stained the apicoplast and mitochondrion of parasites

[HTML][HTML] Toxoplasma gondii Relies on Both Host and Parasite Isoprenoids and Can Be Rendered Sensitive to Atorvastatin

ZH Li, S Ramakrishnan, B Striepen… - PLoS …, 2013 - journals.plos.org
… of precursors for isoprenoids in Apicomplexa occurs in the apicoplast and is essential. To …
Δfpps mutant parasites manage to survive without the production of essential isoprenoids we …

Cell cycle‐regulated vesicular trafficking of Toxoplasma APT1, a protein localized to multiple apicoplast membranes

A Karnataki, A DeRocher, I Coppens… - Molecular …, 2007 - Wiley Online Library
… While Toxoplasma gondii lacks this type of translocator, the N-… apicoplast has been shown
to be indispensable for survivalacid phosphoenolpyruvate is required for the type II fatty acid

[PDF][PDF] Phospholipid-mediated calcium homeostasis in Toxoplasma gondii

A Kuchipudi - 2019 - researchgate.net
… rapidly invade other host cells for survival. These repeated cycles of … Phospholipids have
two fatty acid chains and a phosphate … , apicoplast, Golgi body, displaying compartmentalized …

Plasticity of the Phosphatidylcholine biogenesis in the obligate intracellular parasite Toxoplasma gondii

V Sampels - 2012 - edoc.hu-berlin.de
… are present in the apicoplast and mitochondrion of T. … gondii tachyzoite survival and its
replacement by foreign DNA … which are amphipathic molecules with two fatty acid chains at the sn-…

Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii

SC Nair, CF Brooks, CD Goodman, A Strurm… - Journal of Experimental …, 2011 - rupress.org
… Despite the loss of photosynthesis, the apicoplast is critical for the survival of apicomplexans…
of the parasite. We further showed that carbon import is required for fatty acid synthesis as …

[图书][B] Physiological importance of phospholipid biogenesis in Toxoplasma gondii

B Ren - 2019 - search.proquest.com
biosynthesis is crucial for the successful intracellular survival … The reaction is catalyzed
by type II fatty acid synthase (FASII)… as essential signaling mediators involved in apicoplast

The Apicoplast: A Parasite's Symbiont

L Sheiner, B Striepen - Plastid Biology, 2014 - Springer
parasites, namely they can only replicate and survive inside … ; Toxoplasma gondii, the
causative agent of toxoplasmosis, … gondii engages in vigorous de novo fatty acid synthesis and …