Pharmacological and molecular insight on the cardioprotective role of apigenin

SD Thomas, NK Jha, SK Jha, B Sadek, S Ojha - Nutrients, 2023 - mdpi.com
Apigenin attenuated brain damage and improved neuronal … inactivation, attributing protection
against cellular damage. … cell survival while reciprocating p38/JNK/p53 MAP kinase and …

The use of polyphenols for the treatment of Alzheimer's disease

S Sathya, KP Devi - Role of the mediterranean diet in the brain and …, 2018 - Elsevier
… to neuronal cells via various mechanisms such as mitochondrialvia mitogen-activated
protein kinases (MAPK), extracellular-… Apigenin attenuated copper-induced Aβ toxicity through

Impact of plant-derived flavonoids on neurodegenerative diseases

SL Costa, VDA Silva, C dos Santos Souza… - Neurotoxicity …, 2016 - Springer
… of β-amyloid protein (Aβ) that forms aggregates in neuronal … pretreatment attenuates impairment
of learning and memory through … Moreover, in our studies, it was observed that apigenin

Neuroprotective effect of artichoke-based nanoformulation in sporadic Alzheimer's disease mouse model: focus on antioxidant, anti-inflammatory, and amyloidogenic …

HAS El-Nashar, H Abbas, M Zewail, MH Noureldin… - Pharmaceuticals, 2022 - mdpi.com
apigenin was reported to attenuate copper-mediated β-amyloid-induced neurotoxicity via its
antioxidant … microglial inactivation and over-expression of brain-derived neurotrophic factor (…

[HTML][HTML] Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders-a review

F Ayoobi, A Shamsizadeh, I Fatemi… - Iranian journal of …, 2017 - ncbi.nlm.nih.gov
… and 400 mg/kg) attenuated the disease severity in combination … apigenin (25 μM) could
protect copper-mediated β-amyloid … in vitro cell culture studies (34) and enhances mitochondrial

Nutraceuticals against neurodegeneration: a mechanistic insight

VP Dadhania, PP Trivedi, A Vikram… - Current …, 2016 - ingentaconnect.com
Apigenin attenuates copper-mediated β-amyloid neurotoxicity through antioxidation,
mitochondrion protection and MAPK signal inactivation in an AD cell model. Brain Res., 2013, 1492…

Tilianin mediates neuroprotection against ischemic injury by attenuating CaMKII-dependent mitochondrion-mediated apoptosis and MAPK/NF-κB signaling

H Jiang, J Fang, J Xing, L Wang, Q Wang, Y Wang, Z Li… - Life sciences, 2019 - Elsevier
… versatile biological activities including antioxidant, anti-… Under basic conditions, CaMKII
is squint toward inactivation. … neurological protection via effects on mitochondrial function …

The therapeutic potential of apigenin

B Salehi, A Venditti, M Sharifi-Rad, D Kręgiel… - International journal of …, 2019 - mdpi.com
… has demonstrated the ability to inactivate nuclear factor kappa-… Rats were protected against
myocardial injury by attenuating … , β-amyloid peptide-induced amnesia mouse models were …

… effect of polysaccharide separated from Perilla frutescens Britton var. acuta Kudo against H2O2-induced oxidative stress in HT22 hippocampus cells

EB Byun, EJ Cho, YE Kim, WS Kim… - Bioscience …, 2018 - academic.oup.com
… intracellular Ca 2+ levels leading to MAPKs and NF-κB, as … -dependent attenuation of the
H 2 O 2 -induced neurotoxicity … of various phytochemicals, such as apigenin, curcumin, and …

Dietary polyphenols for treatment of Alzheimer's disease–future research and development

D Sheeja Malar, K Pandima Devi - Current Pharmaceutical …, 2014 - ingentaconnect.com
Apigenin attenuates copper-mediated β -amyloid neurotoxicity through antioxidation,
mitochondrion protection and MAPK signal inactivation in an AD cell model. Brain Res. 2013, 1492…