Exploring Antibiotic Appropriateness and Clinical Outcomes among Adult Intensive Care Unit Patients in Two Tertiary Hospitals in Ethiopia: A Prospective …

Z Tilahun, L Kumsa, M Gebre, H Fisseha, L Chelkeba - 2023 - researchsquare.com
… = 10.7, 95% CI 4.56, 25.1) identi ed as independent risk factors exacerbating ICU mortality.
… This study aimed to assess antibiotic appropriateness and patient outcomes in the ICUs of …

Determinants of inappropriate empirical antibiotic treatment: systematic review and meta-analysis

E Carrara, I Pfeffer, O Zusman, L Leibovici… - International journal of …, 2018 - Elsevier
Appropriate empirical antibiotic treatment is associated with … ), 36 restricted inclusion to the
intensive care unit (ICU), 7 to … including patients with bacteraemia, independent risk factors

[HTML][HTML] Risk factors for multidrug resistant bacteria and optimization of empirical antibiotic therapy in postoperative peritonitis

P Augustin, N Kermarrec, C Muller-Serieys, S Lasocki… - Critical Care, 2010 - Springer
… Univariate analysis was performed using Student's t-test or Wilcoxon's rank sum test, as
appropriate for continuous variables, and the Chi squared or Fisher's exact test, as appropriate, …

[PDF][PDF] Antibiotics in sepsis

PY Bochud, MP Glauser, T Calandra - Intensive Care Med, 2001 - researchgate.net
… and the rapid initiation of appropriate antimicrobial therapy and … of the critically ill ICU patient
with severe sepsis or septic … for treatment of premature neonates with risk factors for sepsis. …

[PDF][PDF] Impact of Empirical Antibiotic Choice on the Clinical Outcomes of Patients Admitted to ICU with Sepsis and Septic Shock

IB Abdalrahman, SN Elgenaid… - American Journal of …, 2020 - researchgate.net
… The most common risk factor for sepsis was recent hospitalization (32%) followed by … and
appropriateness of empirical antibiotic choice on the clinical outcomes of sepsis and septic

Considerations for empiric antimicrobial therapy in sepsis and septic shock in an era of antimicrobial resistance

JR Strich, EL Heil, H Masur - The Journal of Infectious Diseases, 2020 - academic.oup.com
risk factors for a subsequent positive clinical culture included ICU stay, central venous catheter,
receipt of antibiotics… significant reduction in time to appropriate empiric antibiotic therapy, …

Antibiotic decision-making in the ICU

L Parra-Rodriguez… - … and Critical Care Medicine, 2022 - thieme-connect.com
relevance of antibiotic appropriateness, we created a stratified analysis to measure the effect
size of appropriate antibiotics… when presented with patient's risk factors.[35] The problem of …

[HTML][HTML] Empirical decision-making for antimicrobial therapy in critically ill patients

M Ippolito, A Cortegiani - BJA education, 2023 - bjaed.org
… challenging in the context of critical care. It should be guided … treatment, hamper their
usefulness in making decisions about … physician's knowledge of risk factors for MDR pathogen …

[HTML][HTML] … generation cephalosporins unavoidable for empirical therapy of community-acquired pneumonia in adult patients who require ICU admission? A retrospective …

G Hariri, J Tankovic, PY Boëlle, V Dubée… - Annals of Intensive …, 2017 - Springer
… and relevance of the chosen empirical antibiotic therapy … amoxicillin/clavulanate), appropriate
(pathogen cefotaxime susceptible … of risk factors associated with colonization/infection with …

Inappropriate empirical antibiotic treatment in high-risk neutropenic patients with bacteremia in the era of multidrug resistance

G Martinez-Nadal, P Puerta-Alcalde… - Clinical Infectious …, 2020 - academic.oup.com
… performed to identify independent risk factors for mortality in … treatments, shock at onset,
intensive care unit (ICU) … compared to those receiving appropriate empirical antibiotic therapy (36…