… Timely administration of appropriate antibiotic therapy (ie, … is the cornerstone of the
management of serious ICU infections [1]. … on patient-specific risk factors for resistance, and local …

… appropriate empiric antibiotic treatment. Although our results do not exclude a beneficial impact
of empiric antibiotic therapy on ICU … diagnostic testing in the ICU setting may be less than …

… the clinical and economic impact of appropriate antimicrobial therapy and adequate source
control in a population of critically ill, high-risk, ICU patients with microbiologically confirmed …

… mortality in patients with VAP and determined independent risk factors for the same. … course
of ICU confinement. We hypothesize that the appropriate initial empiric use of antibiotics may …

… % had received empirical treatment appropriate for their final … patients with this diagnosis
were treated in an ICU, whereas … Increasing age did not emerge as an independent risk factor. …

… on clinical outcomes after adjustment for independent risk factors for 28-day mortality. …
that appropriate empirical antimicrobial therapy reduces short-term mortality in patients with …

… the trauma ICU, or if they had been transferred from the ICU to … were identified as an
independent risk factor for death (OR, 4.28; … Therefore, the appropriate selection of empiric …

… appropriate therapy on in-hospital mortality. The association between inadequate empirical
antimicrobial therapy as well as other risk factors … ill septic patients on admission to the ICU, …

… were more likely to be admitted to the ICU (p=0·03), have multiple infection sites (p<0·001),
a … the appropriateness of empirical therapy and whether more optimal treatment alternatives …

… The selection of initial antibiotic therapy is based on risk factors for specific pathogens, … In
conclusion, discontinuing antibiotics if appropriate cultures are negative after day 3 as well as …