Determinants of prescription and choice of empirical therapy for hospital-acquired and ventilator-associated pneumonia
… Appropriate empirical antibiotics decreased ICU length of stay by 6 days (26.3±19.8 days
versus 32.8±29.4 days; p = 0.04). The antibiotics … rather than focusing on risk factors for specific …
versus 32.8±29.4 days; p = 0.04). The antibiotics … rather than focusing on risk factors for specific …
Mortality in patients with septic shock by multidrug resistant bacteria: risk factors and impact of sepsis treatments
S Busani, G Serafini, E Mantovani… - Journal of intensive …, 2019 - journals.sagepub.com
… adult patients with septic shock caused by MDR infections admitted to our intensive care unit
(ICU) … However, in our cohort, the appropriateness of initial empirical antibiotic therapy was …
(ICU) … However, in our cohort, the appropriateness of initial empirical antibiotic therapy was …
[HTML][HTML] Failure of target attainment of beta-lactam antibiotics in critically ill patients and associated risk factors: a two-center prospective study (EXPAT)
… Early and appropriate antibiotic dosing is associated with improved clinical outcomes in …
in two ICUs in the Netherlands. We enrolled adult patients treated with the following beta-lactam …
in two ICUs in the Netherlands. We enrolled adult patients treated with the following beta-lactam …
Multidrug-resistant bacteria on critically ill patients with sepsis at hospital admission: Risk factors and effects on hospital mortality
MO Maia, CDG da Silveira, M Gomes… - Infection and Drug …, 2023 - Taylor & Francis
… seven adult patients with sepsis were admitted to the ICU within … appropriateness of the
initial antibiotic therapy. According to our institutional protocol, adult patients with sepsis or septic …
initial antibiotic therapy. According to our institutional protocol, adult patients with sepsis or septic …
Factors associated with suitability of empiric antibiotic therapy in hospitalized patients with bloodstream infections
C Grossman, N Keller, G Bornstein… - Journal of …, 2017 - Taylor & Francis
… The main risk factor for inappropriate initial empiric antibiotic therapy was healthcare-…
Therefore, it may not be applicable to patients hospitalized in intensive care units or surgery …
Therefore, it may not be applicable to patients hospitalized in intensive care units or surgery …
29 What Is the Role of Empirical Antibiotic Therapy in Sepsis?
PS Barie, SR Eachempati - … -Based Practice of Critical Care E …, 2010 - books.google.com
… Risk factors for antibiotic-resistant infection in the case of health care–… Initial antibiotic
therapy was appropriate for 55 patients (49.5%). ICU length of stay was shorter with appropriate …
therapy was appropriate for 55 patients (49.5%). ICU length of stay was shorter with appropriate …
[HTML][HTML] Risk factors of initial inappropriate antibiotic therapy and the impacts on outcomes of neonates with gram-negative bacteremia
SM Chu, JF Hsu, MY Lai, HR Huang, MC Chiang… - Antibiotics, 2020 - mdpi.com
… : Timely appropriate empirical antibiotic plays an important role in critically ill patients with
gram-… onset of gram-negative sepsis from neonates in the neonatal intensive care unit (NICU). …
gram-… onset of gram-negative sepsis from neonates in the neonatal intensive care unit (NICU). …
Antibiotic strategies in severe nosocomial sepsis: why do we not de-escalate more often?
S Heenen, F Jacobs, JL Vincent - Critical care medicine, 2012 - journals.lww.com
… The choice of empirical antibiotic therapy … appropriate empirical antimicrobial treatment
may be improved by using a wider-spectrum microbiological policy at the beginning of the septic …
may be improved by using a wider-spectrum microbiological policy at the beginning of the septic …
[HTML][HTML] Antibiotic prescription patterns in the empiric therapy of severe sepsis: combination of antimicrobials with different mechanisms of action reduces mortality
A Díaz-Martín, ML Martínez-González, R Ferrer… - Critical care, 2012 - Springer
… Appropriate empiric antimicrobial therapy is crucial for the survival of sepsis patients [4, 5].
Formerly, multidrug-resistant pathogens were found almost exclusively in nosocomial …
Formerly, multidrug-resistant pathogens were found almost exclusively in nosocomial …
Systematic review of the impact of appropriate versus inappropriate initial antibiotic therapy on outcomes of patients with severe bacterial infections
… that reported patient mortality during ICU or … patients, early initiation of effective broad-spectrum
empirical therapy may be preferable but should be based on analysis of local risk factors …
empirical therapy may be preferable but should be based on analysis of local risk factors …