Risk factors and adequate management for complications of bevacizumab treatment requiring surgical intervention in patients with metastatic colorectal cancer
JW Bong, JL Lee, CW Kim, YS Yoon, IJ Park… - Clinical colorectal …, 2018 - Elsevier
… days before starting BV treatment, and whether BV was used in the first-line setting for
mCRC were collected to analyze the risk factors for complications requiring surgery. In addition, …
mCRC were collected to analyze the risk factors for complications requiring surgery. In addition, …
Targeted therapy of colorectal cancer: clinical experience with bevacizumab
NH Fernando, HI Hurwitz - The Oncologist, 2004 - academic.oup.com
… Preoperative serum VEGF levels have also been shown to correlate … of bevacizumab in
combination with 5-FU/LV as first-line chemotherapy in patients with metastatic colorectal cancer […
combination with 5-FU/LV as first-line chemotherapy in patients with metastatic colorectal cancer […
The McCAVE trial: vanucizumab plus mFOLFOX‐6 versus bevacizumab plus mFOLFOX‐6 in patients with previously untreated metastatic colorectal carcinoma …
JC Bendell, T Sauri, AC Gracián, R Alvarez… - The …, 2020 - academic.oup.com
… bevacizumab/mFOLFOX‐6. Our results suggest that Ang‐2 is not a relevant therapeutic target
in first‐line … , low Ang‐2 baseline levels correlated with better PFS and OS [15, 16]. These …
in first‐line … , low Ang‐2 baseline levels correlated with better PFS and OS [15, 16]. These …
Metastatic colorectal cancer. First line therapy for unresectable disease
J Aparicio, F Esposito, S Serrano, E Falco… - Journal of clinical …, 2020 - mdpi.com
… or sequentially, strongly correlates with median survival in … arterial hypertension, proteinuria,
arterial thrombotic events, … tumors, first-line treatment should include bevacizumab plus …
arterial thrombotic events, … tumors, first-line treatment should include bevacizumab plus …
Bevacizumab exposure beyond first disease progression in patients with metastatic colorectal cancer: analyses of the ARIES observational cohort study
A Grothey, ED Flick, AL Cohn… - … and drug safety, 2014 - Wiley Online Library
… the approval of bevacizumab for the treatment of first-line mCRC.7 This … on clinical outcomes.
The purpose of this analysis was twofold: to examine whether longer use of BBP correlated …
The purpose of this analysis was twofold: to examine whether longer use of BBP correlated …
[HTML][HTML] Early hypertension is associated with better clinical outcomes in gastric cancer patients treated with ramucirumab plus paclitaxel
N Fukuda, D Takahari, T Wakatsuki, H Osumi… - Oncotarget, 2018 - ncbi.nlm.nih.gov
… Moreover, bevacizumab-induced hypertension is associated … first-line therapy was ≥ 6
months in 22 (25%) patients; nine (… REGARD trial or in colorectal cancer patients who received …
months in 22 (25%) patients; nine (… REGARD trial or in colorectal cancer patients who received …
[HTML][HTML] Hypertension and proteinuria as clinical biomarkers of response to bevacizumab in glioblastoma patients
B Carvalho, RG Lopes, P Linhares, A Costa… - … of Neuro-Oncology, 2020 - Springer
… overall survival (OS) in metastatic colorectal cancer (mCRC) and that … All patients were
treated according to standard first-line … developed during bevacizumab therapy are correlated to …
treated according to standard first-line … developed during bevacizumab therapy are correlated to …
Clinical efficacy and safety of bevacizumab monotherapy in patients with metastatic melanoma: predictive importance of induced early hypertension
C Schuster, HP Eikesdal, H Puntervoll, J Geisler… - PLoS …, 2012 - journals.plos.org
… in colorectal cancer [9] and in non-small cell lung cancer [10]. … progression on standard first
line treatment with dacarbazine (… assessed for subsequent correlation with clinical outcome. …
line treatment with dacarbazine (… assessed for subsequent correlation with clinical outcome. …
[HTML][HTML] Association between ramucirumab-related hypertension and response to treatment in patients with metastatic gastric cancer
G Roviello, SP Corona, AG Multari, G Paganini… - Oncotarget, 2018 - ncbi.nlm.nih.gov
… HTN is correlated with response to second line treatment with … to treatment with bevacizumab
in metastatic colorectal cancer … from the last dose of first-line platinum and fluoropyrimidine …
in metastatic colorectal cancer … from the last dose of first-line platinum and fluoropyrimidine …
Phase II randomized trial of sequential or concurrent FOLFOXIRI‐bevacizumab versus FOLFOX‐bevacizumab for metastatic colorectal cancer (STEAM)
HI Hurwitz, BR Tan, JA Reeves, H Xiong… - The …, 2019 - academic.oup.com
… First‐line treatment for metastatic colorectal cancer (mCRC) typically entails a biologic such
as bevacizumab (… in STEAM had BRAF‐mutated disease to allow correlation with outcomes. …
as bevacizumab (… in STEAM had BRAF‐mutated disease to allow correlation with outcomes. …