Bevacizumab and oxaliplatin-based chemotherapy in metastatic colorectal cancer

GL Beatty, BJ Giantonio - Expert review of anticancer therapy, 2008 - Taylor & Francis
… In metastatic colorectal cancer disease progression correlates with serum VEGF levels. The
… of using bevacizumab in the first-line treatment setting for metastatic colorectal cancer was …

Toxicity of bevacizumab in combination with chemotherapy in older patients

…, A Hurria, Cancer and Aging Research Group. - The …, 2013 - academic.oup.com
… One study evaluating safety of bevacizumab for older colorectal cancer patients found that
use of … (OCS), investigating the use of firstline bevacizumab for metastatic CRC, has included …

[PDF][PDF] The impact of primary tumor localization on survival and treatment outcomes in patients with metastatic colorectal cancer-a multicenter study

S Sahin, F Karatas - J buon, 2019 - jbuon.com
… lacks clinical and molecular biomarkers that correlate with treat… or cetuximab in the first-line
setting were compared. This … left-sided tumors treated with either bevacizumab- or cetuximab…

Temporary blood pressure drop after bevacizumab administration is associated with clinical course of advanced colorectal cancer

M Kanai, H Ishiguro, Y Mori, T Kitano… - … journal of cancer, 2011 - nature.com
… a positive correlation between hypertension after bevacizumab treatment and clinical outcome
(Scartozzi et … In fact, TTF of patients who received bevacizumab as first-line or second-line …

Patterns of care and outcomes for elderly patients with metastatic colorectal cancer in Australia

S Parakh, HL Wong, R Rai, S Ali, K Field… - … of geriatric oncology, 2015 - Elsevier
… 85 years and correlated with potential prognostic factors. … suggests underutilisation of
bevacizumab in older patients, but … ) of patients aged ≥ 65 years received first-line chemotherapy …

Sequential treatment with Bevacizumab and Aflibercept for metastatic colorectal cancer in real-world clinical practice

T Buchler, I Kiss, J Hornova, O Fiala, M Wiesnerova… - Targeted Oncology, 2020 - Springer
… the start of first-line bevacizumab in patients treated with the … with aflibercept in real-world
clinical practice were consistent … a positive correlation between PFS on bevacizumab and PFS …

Spotlight on bevacizumab in metastatic colorectal cancer: patient selection and perspectives

M Bupathi, DH Ahn, T Bekaii-Saab - … cancer: targets and therapy, 2016 - Taylor & Francis
… and an anti-EGFR agent with chemotherapy should not be used in patients treated in first
line with mCRC. Ongoing studies continue to evaluate the role of this strategy in more …

Continuation of bevacizumab after first progression in metastatic colorectal cancer (ML18147): a randomised phase 3 trial

J Bennouna, J Sastre, D Arnold, P Österlund… - … lancet oncology, 2013 - thelancet.com
colorectal cancer progressing up to 3 months after discontinuing first-line bevacizumab plus
… plus chemotherapy beyond first progressive disease correlated with prolonged survival …

… a randomized, biomarker-stratified, phase II study of mFOLFOX6-bevacizumab versus FOLFIRI-bevacizumab as first-line chemotherapy in metastatic colorectal cancer

AR Parikh, FC Lee, L Yau, H Koh, J Knost… - Clinical Cancer …, 2019 - AACR
… -BV had comparable PFS and OS, similar to results in patients with high baseline tumor
ERCC1 levels. There were no new safety signals with these bevacizumab-containing regimens. …

Critical appraisal of bevacizumab in the treatment of metastatic colorectal cancer

F Zoratto, L Rossi, A Zullo, A Papa… - OncoTargets and …, 2012 - Taylor & Francis
… In fact, bevacizumab was studied in diverse combinations of … in first-line treatment of metastatic
colorectal cancer, ie, … studies assessed the correlation between bevacizumab and tumor …