… CPT-11 with LV5FU2 infusion (FOLFIRI-3) in combination with bevacizumab: clinical outcomes in first-line metastatic colorectal cancers according to plasma …

S Kim, E Dobi, M Jary, F Monnien, E Curtit, T NGuyen… - BMC cancer, 2013 - Springer
… -2 at baseline correlate with poor clinical outcomes in patients treated with FOLFIRI3-b … -
bevacizumab was a manageable option in first line metastatic colorectal cancer patients. Indeed…

[HTML][HTML] Angiotensin II type-1 receptor blockers enhance the effects of bevacizumab-based chemotherapy in metastatic colorectal cancer patients

H Osumi, S Matsusaka… - … clinical oncology, 2015 - spandidos-publications.com
clinical outcomes in mCRC patients. The aim of this study was to retrospectively analyze
clinical outcomes in mCRC patients … metastatic colorectal cancer (mCRC) treated with first-line

Clinical significance of hypertension in patients with different types of cancer treated with antiangiogenic drugs

M Dong, R Wang, P Sun, D Zhang… - Oncology …, 2021 - spandidos-publications.com
… are the preferred first-line option in treatment of hypertension … of severe hypertension in
patients with colorectal cancer. … shown that bevacizumab-induced hypertension is related to …

[HTML][HTML] Bevacizumab combined with chemotherapy for patients with advanced colorectal cancer: a systematic review

…, Gastrointestinal Cancer Disease Site Group - Annals of oncology, 2010 - Elsevier
… Currently, the standard first-line treatment of metastatic colorectal cancer in Canada is either
a … The increased expression of VEGF has been correlated with metastasis, recurrence, and …

Incidence and management of bevacizumab-related toxicities in colorectal cancer

MW Saif, R Mehra - Expert opinion on drug safety, 2006 - Taylor & Francis
… monoclonal antibody against vascular endothelial growth … as first-line treatment of metastatic
colorectal cancer (CRC) … does not seem to correlate with hypertension and the role of …

Efficacy and safety of bevacizumab in elderly patients with advanced colorectal cancer: a meta-analysis

X Chen, Y Chen, X Cai, D Zhang, L Fan… - Journal of Cancer …, 2017 - journals.lww.com
… There were 2813 cases in the present study, including 1391 cases treated with bevacizumab
plus CT and 1422 cases treated with single CT. The follow-up time in the present study was …

Bevacizumab treatment in the elderly patient with metastatic colorectal cancer

M Di Bartolomeo, C Maggi, F Ricchini… - Clinical Interventions …, 2015 - Taylor & Francis
… However, in this study, for patients receiving bevacizumab in first line, median OS was … ,
several domains of CGA were demonstrated to correlate with oncological outcomes. Therefore, …

Tolerability on serious adverse events of first-line bevacizumab and cetuximab for RAS wild-type metastatic colorectal cancer: A systematic review and meta-analysis

YN Han, YJ Choi, SJ Rhie - Healthcare, 2022 - mdpi.com
… agents (bevacizumab and cetuximab); … clinical safety of first-line bevacizumab and
cetuximab-based chemotherapy in unresectable RAS wild-type metastatic colorectal cancer patients

[HTML][HTML] Capillary density has no value as an early biomarker of bevacizumab efficacy in metastatic colorectal cancers: a prospective clinical trial

JD Fumet, A Bertaut, L Bengrine, P Lapierre, J Vincent… - Oncotarget, 2018 - ncbi.nlm.nih.gov
… Surprisingly, we found no correlation between blood pressure and … that in phase 3 trials
using bevacizumab in the first line (7.6 months in our cohort … MAP Mean arterial blood pressure

Anti-vascular endothelial growth factor therapy impairs endothelial function of retinal microcirculation in colon cancer patients–an observational study

M Reimann, G Folprecht, R Haase… - … & Translational Stroke …, 2013 - Springer
… Spearman correlation coefficients were calculated between … Patients receiving bevacizumab
as first line treatment (n = 9) … Arterial hypertension is a candidate prognostic biomarker of …