Approaches to Control and Monitor Protease Levels in Chronic Wounds

D Kolahreez, L Ghasemi‐Mobarakeh… - Advanced …, 2024 - Wiley Online Library
… The key point is that the wound investigated in this study may better … Gelatinase activity was
also assessed in this research, and … delivery of doxycycline through microneedle rollers to an …

Zein-maltodextrin nanocomplex based dissolving microneedle: A promising approach for Paliperidone palmitate delivery

VY Londhe, RS Bhadale - International Journal of Biological …, 2023 - Elsevier
Microneedling enhanced the concentration of PLDN in … to replicate human skin in order to
assess whether or not MNs are … M® membrane, a synthetic, non-animal membrane that can be …

A novel versatile animal-free 3D tool for rapid low-cost assessment of immunodiagnostic microneedles

S Totti, KW Ng, L Dale, G Lian, T Chen… - Sensors and Actuators B …, 2019 - Elsevier
… MN rollers for drug delivery purposes [4]. The in vitro tool consisted of a synthetic membrane
placed … resection, and early detection greatly enhances prognosis. An elevated serum 100B …

Brain targeted oral delivery of doxycycline hydrochloride encapsulated Tween 80 coated chitosan nanoparticles against ketamine induced psychosis: behavioral …

M Yadav, M Parle, N Sharma, S Dhingra, N Raina… - … delivery, 2017 - Taylor & Francis
… of pure doxycycline hydrochloride, showing better penetration of … , followed by evaluation of
their antipsychotic activity in … ) and placed in a dialysis membrane bag (molecular weight cut …

Modern ways of doxicycline delivery and prospects of application in pharmacy

OO Saliy, YV Sachenko, TA Palchevska… - Farmatsevtychnyi …, 2022 - pharmj.org.ua
… of doxycycline have now been described as enhancing … analyze modern ways of doxycycline
delivery, to determine the … to inhibit matrix metalloproteinases (MMPs) and antiviral activity, …

Recent update on alginate based promising transdermal drug delivery systems

S Manna, P Gupta, G Nandi, S Jana - Journal of Biomaterials …, 2023 - Taylor & Francis
… by scientists containing a backing membrane and adhesive layer, … Omolu et al. fabricated
solid microneedle roller to enhance … The pharmacokinetic analysis demonstrated enhanced

The role of doxycycline as a matrix metalloproteinase inhibitor for the treatment of chronic wounds

J Stechmiller, L Cowan… - Biological research for …, 2010 - journals.sagepub.com
… to inhibit members of the MMP superfamily like MMPs and TNF-… overview of the roles of MMPs
and intrinsic tissue inhibitors of … doxycycline, a synthetic MMP inhibitor (MMPI), to enhance

Animal tissue-derived biomaterials for promoting wound healing

X Cao, X Lin, N Li, X Zhao, M Zhou, Y Zhao - Materials Horizons, 2023 - pubs.rsc.org
… treatment field based on the evaluation of their critical properties… the CAM (Chicken
Chorioallantoic Membrane) experiment. … to promote direct vascularization in addition to the …

[HTML][HTML] Three-dimensional (3D) printed microneedles for microencapsulated cell extrusion

C Farias, R Lyman, C Hemingway, H Chau, A Mahacek… - Bioengineering, 2018 - mdpi.com
… The specific aim of this study was to assess the viability of … polymeric microneedle fabrication
has enhanced the payload of … membrane and the clinical nature of the latter research. …

Advanced wound diagnostics: toward transforming wound care into precision medicine

MA Weigelt, HA Lev-Tov, M Tomic-Canic… - Advances in Wound …, 2022 - liebertpub.com
MMP expression may also be useful in assessing the … in achieving intradermal delivery of
doxycycline in an in vitro … opsonization, and they promote a chronic inflammatory environment …