… evaluated, interventions, outcomes, and limitations. Outcome prediction in severe brain injury
is reliant on features of the neurologic examination, anatomical and physiological changes …

… critical for therapeutic decisions and outcome. A prospective multicenter study of 1206 patients
… In the present study, we used the GCA scale to assess brain atrophy, finding atrophy in a …

… , assessment of white matter abnormalities and white matter … quantifying the axonal injury
associated with head trauma [15… The authors performed a multicenter prospective cohort study …

… Methods and analysis A prospective cohort multicentre study … assessment (modified Neonatal
Behavioural Assessment Scale). At a CA of 18 months, the motor function will be assessed …

… destruction and remodeling of white matter connectivity. White matter injury can be
noninvasively detected by MRI, which provides a three-dimensional assessment of its morphology, …

… a consequence of the older age of those subjects with more WMH. A more recent study in a
large cohort … The full analysis of these limitations is beyond the remit of this paper, but these …

… of age, witnessed closed head trauma, no focal neurologic deficit, … While our study shows
the potential of PCA in FA analysis, … retrospective cohort; thus, larger, multicenter prospective …

… a prospective multi-centre cohort of patients with severe TBI, … analysis was centred on
anatomical changes in white matter, … to be a fundamental feature in severe TBI [Citation27]. More …

… illnesses possibly interfering with follow-up assessment (n=57), absence of age related
white matter changes (n=27), and inability or refusal to undergo magnetic resonance imaging …

… The 3-City (3C) Study is a multicenter prospective cohort … The current analysis focuses on
the Dijon center participants … In a first step of the study, we assessed a combined outcome …