… The best studied member of this group is the G protein-activated K+ channel found in atria
of all vertebrates. This channel, which we denote KGA, figured in the original discovery of …

… The molecular structures of atrial and neuronal KG channels … that the structure of G-protein-activated
inwardly rectifying K+ … Further studies, such as expression cloning, will help to …

… GIRK4 being essential for functional channels. Moreover, GIRK4 probably regulates …
expression. Although several different cDNA clones of I K1 have been detected in the human atrium …

… ABSTRACT: The muscarinic-gated atrial potassium channel I … Recent cloning efforts have
revealed a large number of … or insect cells yielded G protein-activated inwardly rectifying K + …

… of the molecular details of structure and of gating by G protein … after the cloning of the first
two representatives of the K ir … There is little doubt that the cardiac (atrial) K(ACh) channel is a …

… properties of the IRK1 channel resemble those of the inward … level, we have cloned two kinds
of inwardly rectifying K+chan… Based on the cDNA sequences for the rat C protein-activated …

… This clone is expressed in the atrium of the heart, but not in the ventricle, which is … The
precise properties of this interaction between the KAch channel and … Atria1 G protein-activated …

… genes has led to remarkable progress in our understanding of the molecular structure, …
Atrial G protein-activated K+ channel: Expression cloning and molecular properties. Proc …

… We refer to these cloned channels as KQ1 s instead of the … 5B we have sketched the presumed
structure of KGI and … of the inwardly rectifying G-proteinactivated atrial K" channel (GIRK1) …

… of three additional novel isoforms of GIRK1a from rat atria and … These channels were first
cloned by expression cloning from … LY (1993a) Primary structure and functional expression of a …