Autoantibodies to phosphorylcholine and cardiovascular outcomes in patients with acute coronary syndromes in the ATLAS ACS-TIMI 46 trial

BJ Geller, JL Mega, DA Morrow, J Guo… - Journal of thrombosis …, 2014 - Springer
… Anti-PC autoantibodies have been … cardiovascular outcomes in patients with acute coronary
syndromes (ACS). We measured anti-PC levels within 7 days of an ACS in 3,356 patients

IgM-phosphorylcholine autoantibodies and outcome in acute coronary syndromes

K Caidahl, M Hartford, T Karlsson, J Herlitz… - … journal of cardiology, 2013 - Elsevier
… ) autoantibodies against PC add prognostic information in acute coronary syndromes (ACS). …
Immunoglobulin-M (IgM) autoantibodies against phosphorylcholine (anti-PC) are a putative …

Long-term prognostic value of IgM antibodies against phosphorylcholine for adverse cardiovascular events in patients with stable coronary heart disease

A Imhof, W Koenig, A Jaensch, U Mons, H Brenner… - Atherosclerosis, 2015 - Elsevier
… Low concentrations of IgM-phosphorylcholine autoantibodies (IgM-anti-PC) have …
cardiovascular disease (CVD) events and total mortality in patients suffering from an acute coronary

Autoantibodies against apolipoprotein A‐1 and phosphorylcholine for diagnosis of non‐ST‐segment elevation myocardial infarction

PF Keller, S Pagano, P Roux‐Lombard… - Journal of internal …, 2012 - Wiley Online Library
CV disease risk prediction varies from 17 to 29 U mL −1 according to published reports [15,
16], and because no data are currently available for NSTEMI prediction with this autoantibody

Higher levels of anti-phosphorylcholine autoantibodies in early rheumatoid arthritis indicate lower risk of incident cardiovascular events

S Ajeganova, MLE Andersson, J Frostegård… - Arthritis Research & …, 2021 - Springer
… We hypothesized that the association between IgM anti-PC and the risk of CV outcome is
different in the presence of CV risk factors. We therefore further performed analyses within the …

… against phosphorylcholine measured early after acute ST-elevation myocardial infarction in relation to atherosclerotic disease burden and long-term clinical outcome

EC Knudsen, I Seljeflot, TA Aksnes, J Eritsland… - Plos one, 2019 - journals.plos.org
… and coronary occlusion is the leading underlying cause of myocardial infarction and sudden
cardiacAutoantibodies directed towards a variety of oxidation-specific epitopes or self—…

Low levels of IgM antibodies against phosphorylcholine predict development of acute myocardial infarction in a population-based cohort from northern Sweden

H Grönlund, G Hallmans, JH Jansson… - … Cardiology, 2009 - academic.oup.com
Objective Phosphorylcholine (PC) is one important epitope on oxidized low-density
lipoprotein that may play an important role by contributing to the atherogenicity of oxidized low-…

A role for autoantibodies in atherogenesis

RA Iseme, M McEvoy, B Kelly, L Agnew… - Cardiovascular …, 2017 - academic.oup.com
autoantibody (highest vs. lowest quartiles of autoantibody titer) on cardiovascular outcomes.
… the association between anti phosphorylcholine autoantibodies (anti-PC)- and CVD-related …

Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation

J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
… could be related to the complexity of the LDL-oxidation process where antigens exposed
could vary to some extent, and there may also be differences in methods used for antibody

Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease

J Frostegård - Clinical immunology, 2010 - Elsevier
Atherosclerosis is an inflammatory condition characterised by an abundance of activated
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …