… whether the prognostic benefits induced by sacubitril/valsartan might be mediated by
changes in echocardiographically-defined hemodynamic profiles in ambulatory HFrEF patients. …

… In conclusion, sacubitril/valsartan treatment exerts beneficial hemodynamic effects, including
vasodilatation and blood … It also has a beneficial effect on cardiac remodeling, improving …

… specific therapeutic benefits to patients with heart failure and … Treatment with sacubitril-valsartan
was also associated with … but significant improvement in cardiac function measured by …

… of sacubitril/valsartan in patients with chronic heart failure with … Beneficial hemodynamic
effects of sacubitril/valsartan were … heart valve insufficiency, our data illustrated an improvement …

… improvement in cardiac index garnered from vasoactive agents. We also observed improvement
in … if these properties of maintaining hemodynamic benefit are unique or superior with …

… that treatment with sacubitril/valsartan significantly improved the haemodynamic profile
without concomitant hypotension or worsening renal function. These benefits were apparent at …

… women who derive greater benefit from sacubitril/valsartan. … BP control improved cardiovascular
outcomes, excluded patients … went beyond its hemodynamic effects on BP. For instance, …

… , sacubitril/valsartan is effective in improving outcome across … burden of death and
cardiac-related hospitalizations. It is caused … The benefits of S/V therapy both at intermediate and …

… of sacubitril/valsartan: 1) synergy of sacubitril and valsartan leads to the improvement of
load-dependent left ventricular … In addition, sacubitril/valsartan resulted in better health-related …

… of comorbidities; patient characteristics; hemodynamics; and HF signs … the associated
rationales for investigating alternate markers of … Sacubitril/valsartan improved measures of cardiac …