An unbalanced synaptic transmission: cause or consequence of the amyloid oligomers neurotoxicity?
M Sciaccaluga, A Megaro, G Bellomo… - International Journal of …, 2021 - mdpi.com
… induce NGFR -mediated neuronal death through the p75 neurotrophin receptor, which is
a … NMDA-dependent long term potentiation (LTP) induction in the hippocampal CA1 and …
a … NMDA-dependent long term potentiation (LTP) induction in the hippocampal CA1 and …
Neuroprotective effects of the amylin analog, pramlintide, on Alzheimer's disease are associated with oxidative stress regulation mechanisms
S Patrick, R Corrigan, J Grizzanti… - Journal of …, 2019 - content.iospress.com
… ability of amylin to activate downstream TRPV4 receptors and … Pramlintide reduces H 2 O 2
-mediated endogenous oxidative … in Aβ plaque burden in the hippocampus but not the cortex. …
-mediated endogenous oxidative … in Aβ plaque burden in the hippocampus but not the cortex. …
[HTML][HTML] Amylin receptor: a common pathophysiological target in Alzheimer's disease and diabetes mellitus
W Fu, A Patel, JH Jhamandas - Frontiers in aging neuroscience, 2013 - frontiersin.org
… T2DM mediated hyperinsulinemic/hypoglycemic episodes may produce long-term changes
in brain vasculature, cellular toxicity including inflammation and oxidative stress, alternations …
in brain vasculature, cellular toxicity including inflammation and oxidative stress, alternations …
[HTML][HTML] Lessons from two prevalent amyloidoses—what amylin and Aβ have in common
… of both HA and Aβ 42 mediated via the amylin receptor. … ; in these, Aβ and human amylin
depressed the induced LTP, … human amylin, we found that, different from hippocampal cultures, …
depressed the induced LTP, … human amylin, we found that, different from hippocampal cultures, …
Synapse formation and function is modulated by the amyloid precursor protein
C Priller, T Bauer, G Mitteregger, B Krebs… - Journal of …, 2006 - Soc Neuroscience
… hippocampal neurons lacking APP show significantly enhanced amplitudes of evoked AMPA-
and NMDA-receptor-mediated … in hippocampal slice preparations depressed both AMPA- …
and NMDA-receptor-mediated … in hippocampal slice preparations depressed both AMPA- …
Pathogenesis of Abeta oligomers in synaptic failure
… beta-Amyloid-induced dynamin 1 degradation is mediated … Human amylin oligomer growth
and fibril elongation define … Soluble Aβ oligomers inhibit long- term potentiation through a …
and fibril elongation define … Soluble Aβ oligomers inhibit long- term potentiation through a …
The link between type 2 diabetes and neurodegeneration: roles for amyloid-β, amylin, and tau proteins
P Bharadwaj, N Wijesekara… - Journal of …, 2017 - content.iospress.com
… support the role of amylin in mediating amyloid deposition and … The long-term health of the
cell is inherently linked to protein … Amylin can cross the blood-brain barrier and receptors are …
cell is inherently linked to protein … Amylin can cross the blood-brain barrier and receptors are …
The role of the beta-amyloid peptide in Alzheimer's disease-Mechanisms of toxicity
SR Jansen - 2009 - fse.studenttheses.ub.rug.nl
… , a class of ligand gated ionotropic glutamate receptors which mediate … beta-peptide inhibits
the late phase of longterm potentiation … Amyloid beta and amylin fibrils induce increases in …
the late phase of longterm potentiation … Amyloid beta and amylin fibrils induce increases in …
Survey of CNS Expression of the Amylin Receptor in Health and Metabolic Disease: Potential Relevance to Alzheimer's Disease
SJ Servizi - 2019 - search.proquest.com
… and leptin signaling has been shown to enhance long-term potentiation (… Beta amyloidinduced
depression of hippocampal long-term potentiation is mediated through the amylin receptor…
depression of hippocampal long-term potentiation is mediated through the amylin receptor…
LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent
… surrogate long-term potentiation (LTP), effects that may be mediated by … Beta amyloid-induced
depression of hippocampal long-term potentiation is mediated through the amylin receptor…
depression of hippocampal long-term potentiation is mediated through the amylin receptor…