Blockade of CXCR3 receptor: ligand interactions reduces leukocyte recruitment to the lung and the severity of experimental idiopathic pneumonia syndrome
GC Hildebrandt, LA Corrion, KM Olkiewicz… - The Journal of …, 2004 - journals.aai.org
… + T cells into both cardiac and tracheal allografts in murine models (42, 72). We found that
in contrast to the significant increase of Mig and IP-10 in the BALF after allo-SCT, BALF levels …
in contrast to the significant increase of Mig and IP-10 in the BALF after allo-SCT, BALF levels …
Regulation of pulmonary fibrosis by chemokine receptor CXCR3
… We also examined CXCR3 ligand expression and found increased CXCL10 mRNA expression
… (C) Levels of CXCR3 ligand CXCL10 mRNA in the mouse lungs treated with bleomycin …
… (C) Levels of CXCR3 ligand CXCL10 mRNA in the mouse lungs treated with bleomycin …
A relevant experimental model for human bronchiolitis obliterans syndrome
S Atanasova, M Hirschburger, D Jonigk, M Obert… - The Journal of Heart and …, 2013 - Elsevier
… .14, 15 Two mouse models of orthotopic lung transplantation … motif) ligand 5 (CCL5) and
chemokine (CXC motif) ligand (… , as well as their common receptor CXCR3, is already increased …
chemokine (CXC motif) ligand (… , as well as their common receptor CXCR3, is already increased …
Inhibiting CXCR3-dependent CD8+ T cell trafficking enhances tolerance induction in a mouse model of lung rejection
… the balance in favor of regulatory mechanisms by modulating … adoptive transfer model of
lung rejection that CXCR3-deficient … ligands that mediate the recruitment of Teff through CXCR3 …
lung rejection that CXCR3-deficient … ligands that mediate the recruitment of Teff through CXCR3 …
CXCR3 ligands are associated with the continuum of diffuse alveolar damage to chronic lung allograft dysfunction
MY Shino, SS Weigt, N Li, V Palchevskiy… - American journal of …, 2013 - atsjournals.org
… Our group has previously demonstrated the role of CXCR3/ligand … models with serial
measurement of the CXCR3 ligands as time-dependent covariates, we found that all three ligands …
measurement of the CXCR3 ligands as time-dependent covariates, we found that all three ligands …
CXCR3 in T cell function
JR Groom, AD Luster - Experimental cell research, 2011 - Elsevier
… The tight correlation between CXCR3 expression and Th1 … verified in mouse models, that
CXCR3 and its ligands regulate the … CXCR3 and its ligands in human disease and murine …
CXCR3 and its ligands regulate the … CXCR3 and its ligands in human disease and murine …
Human and murine obliterative bronchiolitis in transplant
JF McDyer - Proceedings of the American Thoracic Society, 2007 - atsjournals.org
… which are ligands that bind through the receptor CXCR3, were … skin transplant model suggest
that CD4 + CD25 + regulatory T … therefore not accounted for in the murine model. However, …
that CD4 + CD25 + regulatory T … therefore not accounted for in the murine model. However, …
Inducible costimulator blockade prolongs airway luminal patency in a mouse model of obliterative bronchiolitis
A KleinJan, MAM Willart, H Kuipers, AJ Coyle… - …, 2008 - journals.lww.com
… their potential to up-regulate the expression of the chemokine receptor CCR7 and to produce
the ligand … deficient for the CXCL10 and CXCL9 receptor CXCR3 ( 38 ). The finding of Th2-…
the ligand … deficient for the CXCL10 and CXCL9 receptor CXCR3 ( 38 ). The finding of Th2-…
[HTML][HTML] The role of CXCR3 and its chemokine ligands in skin disease and cancer
… murine model of obliterative bronchiolitis (48). In this study the authors demonstrated that
blockade of CXCR3 reduced airway obliteration … with CXCR3 can selectively induce regulatory …
blockade of CXCR3 reduced airway obliteration … with CXCR3 can selectively induce regulatory …
Role of CXCL9/CXCR3 chemokine biology during pathogenesis of acute lung allograft rejection
JA Belperio, MP Keane, MD Burdick… - The Journal of …, 2003 - journals.aai.org
… during rejection in murine models of cardiac allograft … . Early chemokine cascades in murine
cardiac grafts regulate … for treatment of obliterative bronchiolitis in heterotopic rat allografts. …
cardiac grafts regulate … for treatment of obliterative bronchiolitis in heterotopic rat allografts. …