PREVENTION OF OBLITERATIVE BRONCHIOLITIS BY JAK 3 INHIBITION WITH CP-690,550 IS ACCOMPANIED BY A DISTINCT GROWTH FACTOR GENE …

S Zhang, M Lau, G Berry, M Larson, G Rousvoal… - …, 2004 - journals.lww.com
regulatory factors in immunity we have used a mouse model wherein infectious regulatory
… Accordingly, blocking the interaction between CXCR3 and its ligands prolongs graft survival…

An official American Thoracic Society research statement: noninfectious lung injury after hematopoietic stem cell transplantation: idiopathic pneumonia syndrome

A Panoskaltsis-Mortari, M Griese… - American journal of …, 2011 - atsjournals.org
… also called obliterative bronchiolitis (OB), and bronchiolitis obliterans … the importance of
CXCR3/ligand biology in this model of IPS. … It was further shown in a murine model of obliterative

CXCR3/CXCR3 ligand biological axis impairs RENCA tumor growth by a mechanism of immunoangiostasis

J Pan, MD Burdick, JA Belperio, YY Xue… - The Journal of …, 2006 - journals.aai.org
… of CXCR3 on circulating mononuclear cells but impaired the CXCR3 ligand chemotactic …
to tumor by increasing circulating CXCR3 ligand levels in a murine model of RCC. Moreover…

Integrating mechanisms of pulmonary fibrosis

TA Wynn - Journal of Experimental Medicine, 2011 - rupress.org
… , CXCR3, and CXCR2 also regulate fibrosis associated with bronchiolitis obliterans syndrome,
by regulating … evaluating the results from individual mouse models, and, most importantly, …

Expression of CXCR3 on mononuclear cells and CXCR3 ligands in patients with metastatic renal cell carcinoma in response to systemic IL-2 therapy

KL Reckamp, RA Figlin, N Moldawer… - Journal of …, 2007 - journals.lww.com
… to be CXCR3 dependent in a murine model. In addition, the … -regulate their expression of
CXCR3 by using systemic high dose IL-2. We investigated the role of CXCR3 and its ligands in …

CXCL10 Gene Expression in the Lung Tissue of Sulfur Mustard-Exposed Patients with Long-Term Pulmonary Complications

M Nikounezhad, T Ghazanfari, N Askari… - Iranian Journal of War …, 2015 - ijwph.ir
… Pathologic manifestations of bronchiolitis, constrictive bronchiolitis, cryptogenic organizing
CXCR3 and its ligands in a murine model of obliterative bronchiolitis: regulation and function

[HTML][HTML] The role of chemokines in acute liver injury

Y Saiman, SL Friedman - Frontiers in physiology, 2012 - frontiersin.org
… –11/CXCR3 axis is unique based on the alternative regulation of its three ligands, which
are … Additionally, in mouse models of chronic disease, CXCR3 is protective through several …

Chemokine expression during development of fibrosis versus resolution in a murine model of granulomatous experimental autoimmune thyroiditis

K Chen, Y Wei, A Alter, GC Sharp… - Journal of leukocyte …, 2005 - academic.oup.com
… CXCL10 and CXCL9 are regulated by IFN-γ and serve as CXCR3 ligands. Levels of … of
CXCR3+ cells in DBA/1 WT versus IFN-γ−/− thyroids, suggesting a functional relationship. An …

Chemokines and their receptors as markers of allograft rejection and targets for immunosuppression

WW Hancock, L Wang, Q Ye, R Han, I Lee - Current opinion in immunology, 2003 - Elsevier
… immune activation in the murine model, including expression of … , the intragraft expression
of CXCR3 and its ligands has been … from patients with post-transplant obliterative bronchiolitis. …

IL-17A is critical for CD8+ T effector response in airway epithelial injury after transplantation

R Zhang, H Fang, R Chen, JC Ochando, Y Ding… - …, 2018 - journals.lww.com
… is closely correlated with obliterative bronchiolitis development. In … and in vivo neutralization
of CXCR3 or its ligands inhibits the … of bronchiolitis obliterans syndrome in a murine model of …