… ), and/or with a combination of MCT1 and MCT4 inhibitors, to target “metabolic symbiosis.” …
a panel of biomarkers to assess metabolic compartmentation in HNSCC primary tumors ( …

… , tumors that utilize a reverse Warburg metabolism are characterized by high MCT1 expression
in tumor cells and high MCT4 … between MCT1 expression and better prognosis in PDAC …

… metabolic symbiosis, by which lactate in cancer cells under hypoxia is exported through
MCT4 and imported by MCT1 … , and their upregulation is associated with poor prognosis [62,63]. …

… mitochondrial function of cells can induce metabolic coupling… High MCT1 expression
in cancer cells and high MCT4 … rates, tumor growth, and higher rates of relapse and death. …

… selective MCT1 and/or MCT4 inhibitors in cancer therapeutics, … biomarker and viable target
for the design of MCT1 inhibitors … effector T cells’ function showed a stemness-promoting role …

… metabolic symbiosis, by which lactate in cancer cells under hypoxia is exported through MCT4
and imported by MCT1 in less … is associated with poor prognosis in prostate cancer. BMC …

… at combating metabolic disorders, and which tumors began to … of the lactate transporters
MCT1 and MCT4, while the … prediction of tumor grades and prognosis in different cancers [70]…

… metabolism and are associated with poor prognosis in solid … were enrolled onto the SMC
Oncology Biomarker study (NCT#… In the current study, not only MCT4 but also MCT1 and MCT2 …

… with the upregulation of MCT1 and MCT4 in expression in CAFs … on MCT1 expression as
well as its functional consequences … -MCT1 patients presented with poorer prognosis compared …

… MCT1 and MCT4 isoforms are strongly associated with the hyperglycolytic phenotype of …
levels in cancer tissues have been reported as a biomarker of malignancy and prognosis (136). …