Cellular receptors, acceptors and clinical implications.

AO Mansilla, RS Argüero, FG Rico… - Archives of medical …, 1993 - europepmc.org
… a specific cell response. Thus, the inductor-receptor binding complex interaction at the cellular
Cellular receptors have been involved in the mechanism of action of several drugs and its …

[HTML][HTML] Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences

VA Fadok, DL Bratton… - The Journal of clinical …, 2001 - Am Soc Clin Investig
… cholesterol and phospholipids from cells to protein acceptors such as apoA-I, appears to …
of pure apoptotic populations by apoptotic cell receptors on DCs is nonstimulatory, whereas …

Stem cell factor receptor/c-Kit: from basic science to clinical implications

J Lennartsson, L Rönnstrand - Physiological reviews, 2012 - journals.physiology.org
… survival, migration, and proliferation depending on the cell type. Signaling from c-Kit is …
targeting this receptor, eg, the clinically used inhibitor imatinib mesylate. Also other clinically used …

Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions.

AM Schmidt, O Hori, J Brett, SD Yan… - … and thrombosis: a …, 1994 - Am Heart Assoc
… integral membrane protein capable of serving as a cell-surface acceptor site for AGEs. …
cellular receptors, and we are exploring these on the basis of the hypothesis that ligand-receptor

Glycoproteins: their structure, biosynthesis and possible clinical implications

H Schachter - Clinical biochemistry, 1984 - Elsevier
… reticulum to the cell surface, and in recognition phenomena such as receptormediated
endocytosis, … The cell surface carbohydrate of some transformed cell lines tends to be more highly …

International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric …

A Christopoulos, JP Changeux, WA Catterall… - Pharmacological …, 2014 - ASPET
receptors, nuclear hormone receptors, and receptor tyrosine kinases. As a consequence, a
vast … that can vary in a target-, ligand-, and cell-/tissue-dependent manner. The current article …

[HTML][HTML] Consequences of cellular cholesterol accumulation: basic concepts and physiological implications

I Tabas - The Journal of clinical investigation, 2002 - Am Soc Clin Investig
… if appropriate extracellular cholesterol acceptors are present. Not depicted here are those
pathways that downregulate the LDL receptor and cholesterol biosynthetic enzymes and those …

Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting

ES Antonarakis, AJ Armstrong, SM Dehm… - Prostate cancer and …, 2016 - nature.com
… exon of AR-V7) splice acceptor. Further, knockdown of these factors impaired splicing of
exon 3 to CE3 but not exons 3 to 4 in LNCaP95, a cell line derived from the parental LNCaP line …

Functional and clinical consequences of mutations in the FSH receptor

J Gromoll, M Simoni, V Nordhoff, HM Behre… - Molecular and cellular …, 1996 - Elsevier
… Beside the transmembrane domain with the typical seven membrane-spanning helices, the
glycoprotein hormone receptors are characterized by a very large extracellular domain in the …

Potential role of the low-density lipoprotein receptor family as mediators of cellular drug uptake

NS Chung, KM Wasan - Advanced drug delivery reviews, 2004 - Elsevier
… ) receptor family and its pharmaceutical implications in the field of drug delivery. The members
of the LDL receptor family are a group of cell surface receptors … , and are acceptors of free …