The role of HDL in plaque stabilization and regression: basic mechanisms and clinical implications

JE Feig, JL Feig, GD Dangas - Coronary artery disease, 2016 - journals.lww.com
… ) receptor 7, which is required for dendritic cell emigration … receptor type BI (SR-BI), the
major HDL receptor on hepatocytes. Hence, RCT can be considered a cycle in which acceptors of …

[HTML][HTML] Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

B György, TG Szabó, M Pásztói, Z Pál, P Misják… - Cellular and molecular …, 2011 - Springer
… We also summarize clinical implications of membrane … The transfer of membrane components
between donor and acceptor … upon activation of cell surface receptors or apoptosis and the …

[HTML][HTML] Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences

VA Fadok, DL Bratton… - The Journal of clinical …, 2001 - Am Soc Clin Investig
… cholesterol and phospholipids from cells to protein acceptors such as apoA-I, appears to …
of pure apoptotic populations by apoptotic cell receptors on DCs is nonstimulatory, whereas …

Oxidative Stress and its Clinical Consequences: Relationship between Diabetes and Cancer

VM Victor, A Hernandez-Mijares… - Anti-Inflammatory & Anti …, 2011 - ingentaconnect.com
… , including electron acceptors, electron donors and hydride acceptors, … have most likely
remained clinically irrelevant for an … at the cellular level by post-receptor molecular mechanisms, …

[PDF][PDF] IPEX as a result of mutations in FOXP3

HJJ van der Vliet… - Clinical and …, 2007 - downloads.hindawi.com
… Apart from its clinical implications, IPEX illustrates the … + regulatory T cells (right), T cell
receptor-(TCR-) mediated activation … As a consequence, activation results in the transcription of a …

Redistribution of accumulated cell iron: a modality of chelation with therapeutic implications

YS Sohn, W Breuer, A Munnich… - Blood, The Journal of …, 2008 - ashpublications.org
… , chelating cell labile iron and donating iron to physiologic acceptors. Most agents in clinical
… step 2), which then binds to transferrin receptors on the cell surface (step 3), concentrates in …

[PDF][PDF] Gallium in bacteria, metabolic and medical implications

C Auger, J Lemire, V Appanna… - Encyclopedia of …, 2013 - academia.edu
cell lines have shown that transferrin-gallium can compete with transferrin-iron for binding
to cell surface transferrin receptors thus inhibiting cellular … The net consequence of gallium’s …

[HTML][HTML] Antibody-drug conjugates for cancer therapy: chemistry to clinical implications

N Dan, S Setua, VK Kashyap, S Khan, M Jaggi… - Pharmaceuticals, 2018 - mdpi.com
cellular cytoxicity (ADCC) and complement-dependent cytotoxicity (CDC) by binding to Fcγ
receptors … Independent functions of mAbs can be an added advantage over the cell killing …

[HTML][HTML] The function and clinical implication of circular RNAs in lung cancer

W Ren, Y Yuan, J Peng, L Mutti, X Jiang - Frontiers in Oncology, 2022 - frontiersin.org
… Circ-FGFR1 enhances the expression of the motif chemokine receptor 4 (CXCR4) via miR-381-3p,
thus promoting NSCLC progression and resistance to anti-programmed cell death 1 (…

The biology and therapeutic implications of HDACs in the heart

TA McKinsey - … Deacetylases: the Biology and Clinical Implication, 2011 - Springer
… At the cellular level, systolic heart failure is associated with … receptors, including the α 1
-adrenergic receptor (α 1 -AR), the endothelin receptor (ET-R) and the angiotensin receptor (AT-R…