Challenges in Identifying New Antimicrobial Agents Effective for Treating Infections with Acinetobacter baumannii and Pseudomonas aeruginosa

LB Rice - Clinical infectious diseases, 2006 - academic.oup.com
… and enterococcal isolates from infections in patients housed in … Pseudomonas aeruginosa
and Acinetobacter baumannii have developed resistance to multiple antimicrobial agents

[HTML][HTML] Developing new therapeutic approaches for treating infections caused by multi-drug resistant Acinetobacter baumannii: Acinetobacter baumannii therapeutics

P Gallagher, S Baker - Journal of Infection, 2020 - Elsevier
… , Acinetobacter baumannii, Pseudomonas aeruginosa, and … baumannii infections, there is
mounting pressure to find new … While A.baumannii remains a major public health challenge

Global Challenge of Multidrug-Resistant Acinetobacter baumannii

F Perez, AM Hujer, KM Hujer, BK Decker… - Antimicrobial agents …, 2007 - Am Soc Microbiol
… but not in Enterobacteriaceae or in Pseudomonas aeruginosa (… baumannii has been identified
and characterized as a … these agents in the treatment of serious Acinetobacter infections

Multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii: resistance mechanisms and implications for therapy

AP Zavascki, CG Carvalhaes, RC Picao… - Expert review of anti …, 2010 - Taylor & Francis
… to antimicrobial drugs currently used for the treatment of … baumannii; however, Spanish
researchers have identified … Considering the issues presented previously, we will further discuss …

Drug Treatment for Multidrug-Resistant Acinetobacter Baumannii Infections

M Bassetti, E Righi, S Esposito, N Petrosillo… - Future …, 2008 - Taylor & Francis
baumannii treatment and the principal issues involved. … The most important finding of the
present study is that ampicillin–… combination with another active antimicrobial agent. Many MDR …

Acinetobacter baumannii Resistance: A Real Challenge for Clinicians

…, LA Padró Alonzo, A Rivera Reséndiz… - Antibiotics, 2020 - mdpi.com
baumannii, with the objective of identifying the most … that effectively escape the effects
of antibacterial drugs [16]. … such as Pseudomonas aeruginosa, Acinetobacter baumannii, …

Recent advances in therapeutic targets identification and development of treatment strategies towards Pseudomonas aeruginosa infections

DRA Sanya, D Onésime, G Vizzarro, N Jacquier - BMC microbiology, 2023 - Springer
… a challenge to the healthcare system due to their resilience against antimicrobial agents
and … , mechanisms involved in biofilm formation and/or biofilm antimicrobial tolerance in P. …

Considerations in Control and Treatment of Nosocomial Infections Due to Multidrug-Resistant Acinetobacter baumannii

C Urban, S Segal-Maurer… - Clinical Infectious Diseases, 2003 - academic.oup.com
baumannii and Pseudomonas aeruginosa. Evidence is … challenging therapeutic quandaries
when treating patients … Finally, the development of new, more potent antibacterial drugs

Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii: mechanisms and epidemiology

A Potron, L Poirel, P Nordmann - … journal of antimicrobial agents, 2015 - Elsevier
… to multiple antibiotics and at the origin of severe infections is … Among the increasingly reported
and commonly identifiedAcinetobacter baumannii and Pseudomonas aeruginosa occupy …

Prospects and challenges of developing new agents for tough Gram-negatives

AL Meyer - Current opinion in pharmacology, 2005 - Elsevier
… of Pseudomonas aeruginosa isolates to these same antibiotics … entirely new targets for
antibacterial drugs could be identified, … cost of developing a new antibacterial agent is not justified …