Quorum‐sensing system in Acinetobacter baumannii: a potential target for new drug development

K Saipriya, CH Swathi, KS Ratnakar… - Journal of applied …, 2020 - academic.oup.com
… and 46% similar to LasI of Pseudomonas aeruginosa. This abaI gene … A clear challenge
facing the field is to determine what … films as anti‐quorum sensing and food antimicrobial agents

Genetic mechanisms of antibiotic resistance and virulence in Acinetobacter baumannii: background, challenges and future prospects

B Chakravarty - Molecular biology reports, 2020 - Springer
baumannii have identified chromosomal regions denoted as … of resistance to many
antimicrobial agents. Many multidrug … baumannii during infection and antimicrobials targeting …

New treatment options for infections caused by multiresistant strains of Pseudomonas aeruginosa and other nonfermenting gram-negative bacilli

A Sanchez, S Gattarello, J Rello - Seminars in respiratory and …, 2011 - thieme-connect.com
… acquired infections are one of the most important challenges … are Pseudomonas aeruginosa
and Acinetobacter baumannii. … can rapidly evade this antimicrobial agent by upregulating …

[HTML][HTML] Current landscape in the discovery of novel antibacterial agents

J Vila, J Moreno-Morales… - … Microbiology and Infection, 2020 - Elsevier
… Despite the urgent need to find new antibacterial products… good activity against
Enterobacteriaceae and non-fermenters such as Pseudomonas aeruginosa and Acinetobacter

[HTML][HTML] New antibiotics for multidrug-resistant bacterial strains: latest research developments and future perspectives

M Terreni, M Taccani, M Pregnolato - Molecules, 2021 - mdpi.com
… This is the case for Pseudomonas aeruginosa, which shows … of new antimicrobial drugs is
outlined by two 2020 reports: “… research for new antibiotics have highlighted some difficulties; …

Current challenges in antimicrobial chemotherapy: the impact of extended-spectrum β-lactamases and metallo-β-lactamases on the treatment of resistant Gram …

MS Helfand, RA Bonomo - Current Opinion in Pharmacology, 2005 - Elsevier
… the development of new antimicrobial agents has almost ground … -resistant Pseudomonas
aeruginosa infections, although … hours to identify the organism and determine its antimicrobial

[HTML][HTML] Clinical data from studies involving novel antibiotics to treat multidrug-resistant Gram-negative bacterial infections

SS Kanj, M Bassetti, P Kiratisin, C Rodrigues… - … of Antimicrobial Agents, 2022 - Elsevier
Acinetobacter baumannii and Pseudomonas aeruginosa are … , and infections are challenging
to treat, often requiring novel … For non-UTI infections or where KPC has been identified, …

Clinical and pathophysiological overview of Acinetobacter infections: a century of challenges

…, RA Bonomo, P Pantapalangkoor… - Clinical microbiology …, 2017 - Am Soc Microbiol
… , such as Pseudomonas aeruginosa and Staphylococcus … an effort to better understand
Acinetobacter baumannii virulence … The antimicrobial agents used to treat Acinetobacter do select …

An insight into MDR Acinetobacter baumannii infection and its pathogenesis: Potential therapeutic targets and challenges

S Singh, S Singh, M Trivedi, M Dwivedi - Microbial Pathogenesis, 2024 - Elsevier
… , Acinetobacter baumannii, Pseudomonas aeruginosa, and … Finding novel antibacterial
agents has become necessary … the lack of effective antibiotics. Traditionally, the creation of …

New antibiotic agents for bloodstream infections

PI Vergidis, ME Falagas - International journal of antimicrobial agents, 2008 - Elsevier
… organisms presents a significant challenge for the practicing … active agent against wild-type
Pseudomonas aeruginosaAcinetobacter baumannii was the causative pathogen in 28/…