Current and future challenges in the development of antimicrobial agents

RP Rennie - Antibiotic resistance, 2012 - Springer
… of antimicrobial agents at the site of infection without causing … for strains of Acinetobacter
baumannii complex isolated primarily … make finding suitable targets for new antimicrobial agents

The antimicrobial peptide ZY4 combats multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii infection

J Mwangi, Y Yin, G Wang, M Yang… - Proceedings of the …, 2019 - National Acad Sciences
… These findings identify ZY4 as an ideal candidate against … for new antimicrobial drugs, only
a few new viable antibiotics … Development of resistance is a great challenge that hampers …

How to kill Pseudomonas—emerging therapies for a challenging pathogen

LN Yaeger, VE Coles, DCK Chan… - Annals of the New …, 2021 - Wiley Online Library
… Some Pseudomonas aeruginosa isolates are resistant to all … In this review, we identify
the mechanisms that P. … models against both Acinetobacter baumannii and species of …

Antimicrobial activity of a novel aminoglycoside, ACHN-490, against Acinetobacter baumannii and Pseudomonas aeruginosa from New York City

D Landman, P Kelly, M Bäcker, E Babu… - … of Antimicrobial …, 2011 - academic.oup.com
… resistant to all commonly used antimicrobial agents pose an … class I integrons were
identified using previously described … makes them formidable therapeutic challenges. Strains …

[HTML][HTML] How to manage Pseudomonas aeruginosa infections

M Bassetti, A Vena, A Croxatto, E Righi, B Guery - Drugs in context, 2018 - ncbi.nlm.nih.gov
challenges for physicians is the adequate treatment of … strain is non-susceptible to all
antimicrobial agents [2]. The emergence of … First identification of Pseudomonas aeruginosa

[HTML][HTML] Carbapenem-resistant Acinetobacter baumannii: A challenge in the intensive care unit

Y Jiang, Y Ding, Y Wei, C Jian, J Liu… - Frontiers in microbiology, 2022 - frontiersin.org
… and treatment of CRAB infection in ICUs have been recognized as a global challenge because
… are difficult to identify. The emergence and popularity of CRAB, which causes pulmonary …

Carbapenem resistance in Acinetobacter baumannii, and their importance in hospital‐acquired infections: a scientific review

M Nguyen, SG Joshi - Journal of applied microbiology, 2021 - academic.oup.com
… are antimicrobial agents that are important in the treatment of … or novel therapeutic strategies
for dealing with challenges … therapy for Pseudomonas aeruginosa and Acinetobacter

Antimicrobial treatment challenges in the era of carbapenem resistance

AM Peri, Y Doi, BA Potoski, PNA Harris… - … and infectious disease, 2019 - Elsevier
… CR GNB and the arrival of new antibiotics. We have reviewed … new antibiotics against CRE
as well as multidrug-resistant (MDR) Pseudomonas aeruginosa and Acinetobacter baumannii

Emerging therapies for multidrug resistant Acinetobacter baumannii

M García-Quintanilla, MR Pulido, R López-Rojas… - Trends in …, 2013 - cell.com
… Thirty years ago infections caused by A. baumannii could be effectively treated with … The
potential use of bacteriophages as antibacterial agents was recognized at almost the same time …

Evolution of antimicrobial resistance among Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae in Brooklyn, NY

D Landman, S Bratu, S Kochar… - … of antimicrobial …, 2007 - academic.oup.com
… site and urinary tract infections in patients from intensive care … and a polymyxin is often the
antimicrobial agent of last resort. … to previously identified ribotypes predominant in our region. …