New drugs for the treatment of complicated intra-abdominal infections in the era of increasing antimicrobial resistance

LS Syue, YH Chen, WC Ko, PR Hsueh - … journal of antimicrobial agents, 2016 - Elsevier
new challenges in treating complicated intra-abdominal … -resistant Pseudomonas aeruginosa,
Acinetobacter baumannii, … resistant organisms are identified from peritoneal cultures in …

The Challenge of overcoming antibiotic resistance in carbapenem-resistant Gram-negative bacteria:“Attack on Titan”

G Mancuso, S De Gaetano, A Midiri, S Zummo… - Microorganisms, 2023 - mdpi.com
… (CRPA), and carbapenem-resistant Acinetobacter baumannii (… one agent from three or more
classes of antimicrobial agents [… Carbapenemase resistance in P aeruginosa can also occur …

Repurposing of Drugs for Antibacterial Activities on Selected ESKAPE Bacteria Staphylococcus aureus and Pseudomonas aeruginosa

B Kamurai, M Mombeshora… - International Journal of …, 2020 - Wiley Online Library
… therapeutic challenges for the treatment of community and hospital-acquired infections [11]. …
are a good source of antimicrobial agents against bacteria, viruses, and protozoa [22]. …

Discovery and development of new antibacterial agents targeting Gram-negative bacteria in the era of pandrug resistance: is the future promising?

MGP Page, K Bush - Current Opinion in Pharmacology, 2014 - Elsevier
… creating problems of their own, with Pseudomonas aeruginosa and Acinetobacter baumannii
being … from Tetraphase are working to identify novel tetracycline derivatives for treatment of …

Multidrug-resistant Acinetobacter baumannii as an emerging concern in hospitals

S Ibrahim, N Al-Saryi, IMS Al-Kadmy, SN Aziz - Molecular biology reports, 2021 - Springer
… strains resistant to antimicrobial agents are a major challenge for … baumannii can be identified
by using 16 s ribosomal RNA as well … and Pseudomonas aeruginosa. These enzymes can …

[HTML][HTML] What Is New in the Anti–Pseudomonas aeruginosa Clinical Development Pipeline Since the 2017 WHO Alert?

S Reig, A Le Gouellec, S Bleves - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
… to the approval of new antibacterial drugs that treat CRPA in … challenge for obtaining a good
vaccine is the identification of … aureus and Acinetobacter baumannii. TP102 started a safety …

Therapeutic options for Acinetobacter baumannii infections

J Vila, J Pachón - Expert opinion on pharmacotherapy, 2008 - Taylor & Francis
Acinetobacter baumannii resistant to all antimicrobial agents with the … or infected by
multidrug-resistant Pseudomonas aeruginosa … Another interesting finding from this study was that …

The challenges of antimicrobial resistance in Brazil

F Rossi - Clinical infectious diseases, 2011 - academic.oup.com
… The most important finding of this study was that ampicillin-… been restricted for the treatment
of ABC infection for >10 years… lack of new drugs to treat carbapenem-resistant ABC infection, …

[HTML][HTML] The “old” and the “newantibiotics for MDR gram-negative pathogens: for whom, when, and how

I Karaiskos, S Lagou, K Pontikis, V Rapti… - Frontiers in public …, 2019 - frontiersin.org
… , Acinetobacter baumannii, and Pseudomonas aeruginosa (1, … and the lack of new effective
antimicrobial agents (15). The … minor toxicity issues and a challenging antimicrobial spectrum …

Management of infections caused by multidrug-resistant gram-negative pathogens: recent advances and future directions

M Bassetti, A Vena, DR Giacobbe… - Archives of medical …, 2021 - Elsevier
… specific challenges to effective therapy with old antibiotics, … , MDR Pseudomonas aeruginosa
and MDR Acinetobacter … administer at least two antimicrobial agents from different classes, …