[HTML][HTML] MST1 controls murine neutrophil homeostasis via the G-CSFR/STAT3 axis

S Masgrau-Alsina, LM Wackerbarth, D Lim… - Frontiers in …, 2022 - frontiersin.org
… In humans, G-CSF serum levels are nearly undetectable … in emergency granulopoiesis
through the promotion of SOCS3 … next investigated the defective G-CSF-induced mobilization of …

[HTML][HTML] Low density granulocytes in ANCA vasculitis are heterogenous and hypo-responsive to anti-myeloperoxidase antibodies

A Ui Mhaonaigh, AM Coughlan, A Dwivedi… - Frontiers in …, 2019 - frontiersin.org
… -CSF) on human CD16 granulocyte expression, we generated … related gene expression in
AAV overlapped with LDG gene … the LDG population during emergency granulopoiesis in the …

G-CSF maintains controlled neutrophil mobilization during acute inflammation by negatively regulating CXCR2 signaling

B Bajrami, H Zhu, HJ Kwak, S Mondal, Q Hou… - Journal of Experimental …, 2016 - rupress.org
regulation characterized by accelerated granulopoiesis and G-… Our results indicate that
G-CSFinduced inhibition of CXCR2 … eGFP gene expression was achieved by breeding eGFP …

C/EBP Bypasses Granulocyte Colony-Stimulating Factor Signals to Rapidly Induce PU. 1 Gene Expression, Stimulate Granulocytic Differentiation, and Limit …

X Wang, E Scott, CL Sawyers… - Blood, The Journal of …, 1999 - ashpublications.org
… and PU.1 regulate additional genes besides cytokine receptors required for granulopoiesis.
… increased G-CSFR RNA levels observed during G-CSFinduced differentiation (see Fig 4B). …

[HTML][HTML] G-CSF and neutrophils are nonredundant mediators of murine experimental autoimmune uveoretinitis

GL Goldberg, AL Cornish, J Murphy, ES Pang… - The American journal of …, 2016 - Elsevier
… a murine model of human uveitis–experimental autoimmune … , in a response known as
emergency granulopoiesis. G-CSF … G-CSFinduced changes in chemokine receptor expression, …

IFNγ induces monopoiesis and inhibits neutrophil development during inflammation

AM de Bruin, SF Libregts, M Valkhof… - Blood, The Journal …, 2012 - ashpublications.org
gene expression in response to cytokines. The occurrence of … granulocyte colony formation
from human progenitor cells in vitro, … to suppress G-CSFinduced emergency granulopoiesis. …

Defective G-CSFR signaling pathways in congenital neutropenia

J Skokowa, K Welte - Hematology/Oncology Clinics, 2013 - hemonc.theclinics.com
… abnormal granulopoiesis downstream of the ELANE or HAX1 mutations. mRNA expression
… Therefore, the authors concluded that HCLS1 and HAX1 are important for G-CSF-induced F-…

Role for Granulocyte Colony‐Stimulating Factor in Neutrophilic Extramedullary Myelopoiesis in a Murine Model of Systemic Juvenile Idiopathic Arthritis

B Malengier‐Devlies, E Bernaerts… - Arthritis & …, 2022 - Wiley Online Library
… an important role for G-CSFinduced myelopoiesis and … showed an inflammatory gene
expression and primed phenotype (… Second, when studying extramedullary granulopoiesis in the …

[PDF][PDF] The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis

N Ikeda, H Kubota, R Suzuki, M Morita, A Yoshimura… - Cell Reports, 2023 - cell.com
… precursors in terms of gene expression levels, we performed … leads to a disruption in
emergency granulopoiesis.Our RNA-… Surprisingly, we found that G-CSF induced the proliferation …

[HTML][HTML] IL-1 Coordinates the Neutrophil Response to C. albicans in the Oral Mucosa

S Altmeier, A Toska, F Sparber, A Teijeira… - PLoS …, 2016 - journals.plos.org
… (F) IL-1α and IL-1β mRNA expression in the tongues of naïve … mice is sufficient to drive
emergency granulopoiesis as we and … emergency granulopoiesis, mice were injected with human