… , an interaction between copper and hepcidin had not been … characterize metal ion binding
to hepcidin and, using mutation analysis, determine the critical amino acids within hepcidin …

… hepcidin. Our study focused on the model DTHFPI-NH 2 hexapeptide reflecting the N-terminal
motif of mature hepcidin… Based on these results we propose that hepcidin could exist as Cu…

… (5R-hepcidin). … hepcidin we demonstrated that hepcidin can compete for Cd(II) ions with
metallothionein-2, a cellular cadmium target. This study enabled us to conclude that hepcidin …

… To our knowledge, none of the materials used for hepcidin analysis have been characterized
in this respect, yet. Even simple (non-chiral) amino acid analysis can be very useful for the …

Identification of new players in iron metabolism, such as hepcidin, which regulates
ferroportin and divalent metal transporter 1 expression, has improved our knowledge of iron …

… Hepcidin is an iron regulatory hormone that does not bind iron directly. Instead, its mature
25… The Cu(II)-hepcidin complex was previously studied, but due to poor solubility and difficult …

… of hepcidin and the current state-of-the-art in hepcidin assays. We furthermore summarize
human studies of hepcidin in … characterized by increased erythropoietic activity. A decrease in …

… of hepcidin ie, hepcidin 20, 22 and 25. Hepcidin 20 and 22 are the truncated hepcidin having
… ACD is characterized by normocytic normochromic red cells, decreased serum iron levels …

… and mechanistic properties of ill-characterized metalloproteins at … hepcidin without evidence
of transition metal binding [64]. Similarly, production of C-terminal histidine-tagged hepcidin …

… systems are the most well characterized to date and are … hepcidin to inhibit iron transport
into the bloodstream [36]. … The hCP heterodimer has two transition metal-binding sites …