Animal models of carcinogenesis in inflamed colorectum: potential use in chemoprevention study

T Tanaka - Current drug targets, 2012 - ingentaconnect.com
… Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors for primary prevention
of colorectal cancer: a systematic review prepared for the US Preventive Services Task …

[图书][B] Chemoprevention and therapy of Mammary Carcinogenesis by Prostaglandin H Synthase-2 (COX-2) inhibition

GA Alshafie - 2001 - search.proquest.com
in colon cancer. The higher potency and lower toxicity of COX-2 inhibitors offer
chemopreventive/… and chemotherapeutic evaluation of Celecoxib, a cyclooxygenase-2(COX-2) …

Natural COX-2 inhibitors as promising anti-inflammatory agents: an update

J Cui, J Jia - Current Medicinal Chemistry, 2021 - ingentaconnect.com
… , a few dietary COX-2 inhibitors from nature origin also exhibited chemopreventive effects
by … Screening and isolation of cyclooxygenase-2 inhibitors from Trifolium pratense L. via …

Cancer chemoprevention: progress and promise

SM Lippman, JJ Lee, AL Sabichi - … of the National Cancer …, 1998 - academic.oup.com
… The colorectal cancer subset analysis found an RR of 0.42 (95% CI = 0.18–0.95) with …
chemopreventive agents such as cyclooxygenase-2 inhibitors and fenretinide ( 71 , 107 , 108 ). …

Primary and secondary prevention of colorectal cancer

PJT López, JS Albero… - Clinical Medicine …, 2014 - journals.sagepub.com
… risk of colorectal polyps. High calcium intake offers a protector effect against distal colon and
rectal tumors as compared with the proximal colon. … use of various chemoprevention agents. …

Profiles of COX-2 inhibitors: present and future

S Chung, KM Lim, SS Shin - Expert Opinion on Therapeutic Patents, 2005 - Taylor & Francis
… Increased expression of COX-2 was detected in colorectal carcinoma tis… the chemopreventive
activity of NSAIDs or COX-2 inhibitors against … cyclooxygenase-2 inhibitor in cancer

A way forward for cancer chemoprevention: think local

L Al Rabadi, R Bergan - Cancer Prevention Research, 2017 - AACR
Colorectal Induces apoptosis and interrupts prostaglandin production through selective
inhibition of the cyclooxygenase-2 … and mortality risk of colorectal cancer that would complement …

Cancer chemoprevention: a rapidly evolving field

WP Steward, K Brown - British journal of cancer, 2013 - nature.com
… , prostate and colon cancer. The paradigm for developing new chemopreventive agents has
… This review will summarise the current status of the field of chemoprevention and highlight …

Aspirin prevention of colorectal cancer: focus on NF-κB signalling and the nucleolus

J Chen, LA Stark - Biomedicines, 2017 - mdpi.com
… late stage colorectal cancer (TNM stage III–IV) and a worse overall 3 and 5-year survival [59].
Transgenic mice with constitutively active IKK in intestinal epithelial cells develop intestinal

Cyclooxygenase-2: its rich diversity of roles and possible application of its selective inhibitors

M Katori, M Majima - Inflammation Research, 2000 - Springer
Inhibition by NSAIDs of the growth of colon tumors induced by chemical carcinogens in rodents
and the regression, induced by sulindac, of large-bowel … patients with colon cancer who …