Coronavirus infection and cholesterol metabolism

J Dai, H Wang, Y Liao, L Tan, Y Sun, C Song… - Frontiers in …, 2022 - frontiersin.org
… membranes, host cell cholesterol is targeted by pathogens (… membranes, cholesterol
accumulation in lymphoid organs … in cholesterol metabolism in CD11c + immune cells resulted in …

[PDF][PDF] Pathogenesis of nonalcoholic steatohepatitis: an overview

G Parthasarathy, X Revelo… - Hepatology …, 2020 - Wiley Online Library
cholesterol accumulation in hepatocytes and cholesterol … DCs have focused on total CD11c+
or major histocompatibility … (103) Vanin-1-enriched EVs were targeted to endothelial cells

Effects of a high cholesterol diet on the pathogenesis of influenza A virus infection in mature mice

AY Louie - 2021 - ideals.illinois.edu
cells in the lymph node or be targeted for destruction. … autoimmune disorders are often
associated with reduced levels of HDL95-97. … amplifies cholesterol accumulation and activation of …

Effects of Dyslipidemia on Invariant Natural Killer T Cell Activation

NA Braun - 2011 - ir.vanderbilt.edu
… from the aspect of cells important for cholesterol homeostasis and … cells by using a targeted
deletion of the Jα18 gene in LDLr … C, CD11c+ dendritic cells were purified from spleens of B6 …

De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or …

P Stüve, L Minarrieta, H Erdmann… - Frontiers in …, 2018 - frontiersin.org
… of LBs relies on the induction of de novo cholesterol and fatty … the targeting efficiency of
the CD11c cre and LysM cre … exons are targeted for deletion (37). We crossed them with …

2015 russell ross memorial lecture in vascular biology: Protective autoimmunity in atherosclerosis

K Ley - Arteriosclerosis, thrombosis, and vascular biology, 2016 - Am Heart Assoc
… The blood level of LDL cholesterol is the best known biomarker … under the CD11c promoter.
This means that dendritic … Animal experiments with intranasal and oral vaccines targeted to …

Innate and adaptive immunity: the understudied driving force of heart valve disease

F Bartoli-Leonard, J Zimmer… - Cardiovascular research, 2021 - academic.oup.com
… of valve disease is complex, involving genetic factors, lipid … Moreover, the accumulation of
macrophages to the valve … more investigated roles of immune cells within atherosclerosis with …

Atherosclerosis: orchestrating cells and biomolecules involved in its activation and inhibition

A Munjal, R Khandia - Advances in protein chemistry and structural biology, 2020 - Elsevier
… a cholesterol-rich diet fed mice model, foam cells were found positive for DC markers CD11c,
… The unstable plaque rupture is the causative of symptomatic coronary thrombosis and can …

Mechanisms of inflammation modulation by different immune cells in hypertensive nephropathy

X Hao, Y Liu, D Hailaiti, Y Gong, X Zhang… - Frontiers in …, 2024 - frontiersin.org
… , as depletion of CD11c+ cells ameliorates antibody-induced … The accumulation of immune
cells in the kidneys promotes a … therapeutic regimens and develop targeted drugs in the future…

[PDF][PDF] The mevalonate pathway is a druggable target for vaccine adjuvant discovery

Y Xia, Y Xie, Z Yu, H Xiao, G Jiang, X Zhou, Y Yang… - Cell, 2018 - cell.com
… unrelated to the terminal cholesterol-lowing effects; rather, it is … reductase (targeted by statins)
and FPPS (targeted by TH-… immune cells isolated from GGPPSfl/fl/CD11c-cre and CD11c