[HTML][HTML] Co-amorphous solid dispersion systems of lacidipine-spironolactone with improved dissolution rate and enhanced physical stability
Z Wang, M Sun, T Liu, Z Gao, Q Ye, X Tan… - Asian Journal of …, 2019 - Elsevier
… -ASDs systems and to select the optimal molar ratio of LCDP and SPL for maintaining good
physical … system (1:6), due to the residual ethanol in the C-ASDs system prepared by solvent …
physical … system (1:6), due to the residual ethanol in the C-ASDs system prepared by solvent …
[HTML][HTML] A comparison of spray-drying and co-precipitation for the generation of amorphous solid dispersions (ASDS) of hydrochlorothiazide and simvastatin
M Myślińska, MW Stocker, S Ferguson… - Journal of Pharmaceutical …, 2023 - Elsevier
… choice of manufacturing method. The results presented in this article aim to inform the selection
of aforementioned two solvent-… , and stability of ASDs prepared via co-precipitation and …
of aforementioned two solvent-… , and stability of ASDs prepared via co-precipitation and …
[HTML][HTML] Advances in the development of amorphous solid dispersions: The role of polymeric carriers
J Zhang, M Guo, M Luo, T Cai - Asian Journal of Pharmaceutical Sciences, 2023 - Elsevier
… ASDs from the perspectives of physicochemical characteristics of polymers, formulation
designs and preparation … polymers in forming ASDs, selecting an appropriate polymer is usually …
designs and preparation … polymers in forming ASDs, selecting an appropriate polymer is usually …
Patterns of drug release as a function of drug loading from amorphous solid dispersions: A comparison of five different polymers.
… for rational selection of polymers for formulation of ASDs with … drug release from ASDs of a
model drug, felodipine, prepared with … by solvent evaporation using a rotary evaporator (Buchi …
model drug, felodipine, prepared with … by solvent evaporation using a rotary evaporator (Buchi …
Improved solubility, dissolution rate, and oral bioavailability of main biflavonoids from Selaginella doederleinii extract by amorphous solid dispersion
B Chen, X Wang, Y Zhang, K Huang, H Liu, D Xu… - Drug Delivery, 2020 - Taylor & Francis
… to select the optimum carrier for TBESD-ASD using the solvent evaporation method. Finally,
the ASD … In the current research, the preparation conditions of the ASD, including the ethanol …
the ASD … In the current research, the preparation conditions of the ASD, including the ethanol …
Water-induced phase separation of spray-dried amorphous solid dispersions
N Li, JL Cape, BR Mankani, DY Zemlyanov… - Molecular …, 2020 - ACS Publications
… solvent system caused a minor extent of phase separation. Phase heterogeneity in the 50
and 75% drug loading ASDs prepared from this spray solvent can … was not able to pick up two …
and 75% drug loading ASDs prepared from this spray solvent can … was not able to pick up two …
Amorphous solid dispersions (ASDs): The influence of material properties, manufacturing processes and analytical technologies in drug product development
R Iyer, V Petrovska Jovanovska, K Berginc, M Jaklič… - Pharmaceutics, 2021 - mdpi.com
… processes on the selection and design of amorphous solid dispersion (ASD) products as …
thin film ASD prepared by solvent evaporation. DMA can be used for identification of proper …
thin film ASD prepared by solvent evaporation. DMA can be used for identification of proper …
Solubility enhanced formulation approaches to overcome oral delivery obstacles of PROTACs
F Pöstges, K Kayser, J Appelhaus, M Monschke… - Pharmaceutics, 2023 - mdpi.com
… selection of commonly used ASD polymers were conducted, and only the promising polymers
were used for ASD preparation … prepared by dissolving ARCC-4 in the organic solvents, …
were used for ASD preparation … prepared by dissolving ARCC-4 in the organic solvents, …
Solvent-assisted hot melt extrusion of a thermally labile, high melting point compound
C Lagan, JE Huckle, JM Katz, B Khorsand, D Daurio… - AAPS …, 2021 - Springer
… -intensive process, which can become an important deciding factor due to organic solvents
… In this work, a new approach is presented, utilizing HME technology to prepare an ASD of …
… In this work, a new approach is presented, utilizing HME technology to prepare an ASD of …
[HTML][HTML] Physical stability and dissolution of lumefantrine amorphous solid dispersions produced by spray anti-solvent precipitation
… In this study, the feasibility of preparing ASDs by an anti-solvent precipitation method was …
low-cost anti-solvent precipitation approach could be an affordable choice to prepare ASDs of …
low-cost anti-solvent precipitation approach could be an affordable choice to prepare ASDs of …