Intermittent hypoxia therapy ameliorates beta-amyloid pathology via TFEB-mediated autophagy in murine Alzheimer's disease
X Wang, Y Xie, G Chen, Y Lu, D Wang… - Journal of …, 2023 - Springer
… function by effectively activating TFEB in the brain of 3xTg AD model mice [31]. In our study,
… Citalopram improved spatial memory and synaptic plasticity in the hippocampus of AD mice, …
… Citalopram improved spatial memory and synaptic plasticity in the hippocampus of AD mice, …
The role of omega-3 polyunsaturated fatty acids eicosapentaenoic and docosahexaenoic acids in the treatment of major depression and Alzheimer's disease: Acting …
… Similar to DHA, EPA modulates synaptic plasticity by activating … The amelioration in GDS
scores and AA/EPA ratio was … plus citalopram therapy was more effective than citalopram …
scores and AA/EPA ratio was … plus citalopram therapy was more effective than citalopram …
Abnormal circadian locomotor rhythms and Per gene expression in six-month-old triple transgenic mice model of Alzheimer's disease
M Wu, F Zhou, X Cao, J Yang, Y Bai, X Yan, J Cao… - Neuroscience …, 2018 - Elsevier
… We further observed that 3xTg-AD female mice showed obviously less CRD compared
with the 3xTg-AD male mice, and female mice of both WT and 3xTg-AD were more active in …
with the 3xTg-AD male mice, and female mice of both WT and 3xTg-AD were more active in …
Therapeutic Strategies Aimed at Improving Neuroplasticity in Alzheimer Disease
MF Colavitta, FJ Barrantes - Pharmaceutics, 2023 - mdpi.com
… Neuroplasticity, also called brain plasticity or simply plasticity, … with an improvement in
spatial memory. As compared to … Citalopram is another antidepressant that can ameliorate Aβ …
spatial memory. As compared to … Citalopram is another antidepressant that can ameliorate Aβ …
Therapeutics of neurotransmitters in Alzheimer's disease
R Kandimalla, PH Reddy - Journal of Alzheimer's Disease, 2017 - content.iospress.com
… contributing uniquely to synaptic plasticity, activates signaling … and tangle levels in brains of
3xTgAD mice [66]. Notably, tau … induced toxicity, gradual amelioration of memory deficits [71], …
3xTgAD mice [66]. Notably, tau … induced toxicity, gradual amelioration of memory deficits [71], …
Escitalopram ameliorates forskolin-induced tau hyperphosphorylation in HEK239/tau441 cells
QG Ren, YJ Wang, WG Gong, QD Zhou, L Xu… - Journal of Molecular …, 2015 - Springer
… To determine whether the decreased tau phosphorylation was due to the pharmacological
action of escitalopram or its characteristic structure, we treated the cells with R-citalopram, …
action of escitalopram or its characteristic structure, we treated the cells with R-citalopram, …
Some candidate drugs for pharmacotherapy of Alzheimer's disease
B Miziak, B Błaszczyk, SJ Czuczwar - Pharmaceuticals, 2021 - mdpi.com
… as well as baseline synaptic transmission and synaptic plasticity, … alone significantly increased
spatial memory consolidation and … [14] evaluated the effect of citalopram on mitochondrial …
spatial memory consolidation and … [14] evaluated the effect of citalopram on mitochondrial …
Role of σ1 Receptors in Learning and Memory and Alzheimer's Disease-Type Dementia
T Maurice, N Goguadze - Sigma Receptors: Their Role in Disease and as …, 2017 - Springer
… role on brain plasticity and particularly learning and memory … and DTG ameliorated
learning impairments and prevented … , paroxetine, sertraline, citalopram and escitalopram, the …
learning impairments and prevented … , paroxetine, sertraline, citalopram and escitalopram, the …
Involvement of brain-derived neurotrophic factor signaling in the pathogenesis of stress-related brain diseases
T Numakawa, R Kajihara - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
… of iron with classical antidepressants (citalopram or imipramine). It was … Amelioration of
memory impairment in … , oxidative stress, and deficits in synaptic plasticity, all of which are …
memory impairment in … , oxidative stress, and deficits in synaptic plasticity, all of which are …
[HTML][HTML] Histone deacetylases (HDACs) and brain function
CH Volmar, C Wahlestedt - Neuroepigenetics, 2015 - Elsevier
… in spatial memory but crucial for fear memory formation. Other … Such an effect on synaptic
plasticity is inherently linked to … to increase acetylation and ameliorate cognition by modulating …
plasticity is inherently linked to … to increase acetylation and ameliorate cognition by modulating …