Emerging biology of vascular wall progenitor cells in health and disease

D Tilki, HP Hohn, B Ergün, S Rafii, S Ergün - Trends in molecular medicine, 2009 - cell.com
… EPCs are defined as cells that show clonal expression, stemness characteristics, … blood
islands within the yolk sac wall, is supported by recent in vivo studies using mouse models [ …

Hemogenic endothelium: origins, regulation, and implications for vascular biology

JP Zape, AC Zovein - Seminars in cell & developmental biology, 2011 - Elsevier
… Large scale clonal analysis of entire embryos suggested a … reveals the relative contributions
of the ventral blood islands (VBI… (C) In the murine model, assays that compare the yolk sac to …

Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers

JM Tsai, R Sinha, J Seita, N Fernhoff, S Christ… - Science translational …, 2018 - science.org
… the lack of an identifiable cell of origin. Using clonal analysis and lineage tracing, we have
… mesothelial cells from injured mesothelium revealed aspects of the pathological mechanism …

[HTML][HTML] Generation of kidney from pluripotent stem cells via blastocyst complementation

J Usui, T Kobayashi, T Yamaguchi, AS Knisely… - The American journal of …, 2012 - Elsevier
… Retrospective genotyping in a small population revealed that mice with … composed of cells
of polyclonal origin in mouse chimeras. … clonal origins in yolk sac hematopoiesis and germ cell …

Deconvoluting the ontogeny of hematopoietic stem cells

IM Samokhvalov - Cellular and molecular life sciences, 2014 - Springer
… The preimplantation mouse embryo can be drastically … of chicken and mouse blood
islands reveals rather unelaborate … system, and clonal analysis suggested that hemogenic …

Development of the definitive hematopoietic hierarchy in the mouse

AL Medvinsky, EA Dzierzak - Developmental & Comparative Immunology, 1998 - Elsevier
… No yolk sac blood islands or blood vessels are formed and numbers of … Polyclonal antibodies
to β1 can block the formation of CFU-S … as revealed by the following mouse mutants. These …

Intestinal cancer stem cells marked by Bmi1 or Lgr5 expression contribute to tumor propagation via clonal expansion

H Yanai, N Atsumi, T Tanaka, N Nakamura, Y Komai… - Scientific Reports, 2017 - nature.com
Clonal analysis using ubiquitous multicolor lineage tracing revealed that colon tumors …
that the polyclonal origin of colon tumors is just not detected because the models used in this …

[PDF][PDF] Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development

KYC Lau, H Rubinstein, CW Gantner, R Hadas… - Cell Stem Cell, 2022 - cell.com
… cell, single-structure analysis reveals a robust recapitulation of cell … From the four clones we
tested, we selected the clone with the … As we had observed blood islands on the yolk-sac-like …

Isolation and characterization of endothelial progenitor cells from mouse embryos

AK Hatzopoulos, J Folkman, E Vasile… - …, 1998 - journals.biologists.com
… RNA analysis revealed that the embryonic cells express the … the initial stage of blood island
formation. Shortly thereafter, … rabbit polyclonal antibody (DAKO) that cross-reacts with murine

[PDF][PDF] Emergence of Human Angiohematopoietic Cells in Normal Development and from Cultured Embryonic Stem Cells

B PEAULT - academia.edu
… progenitors arise in yolk sac blood islands and mouse EBs as flk-1/… , we revealed this
progenitor after developing an in vitro … If confirmed by clonal analyses currently in progress, these …