… , the impact of multiple genetic risk variants for CVD and/or CKD … In this study, we genotyped
39 SNPs related to kidney disease … of genetic susceptibility to kidney damage also in type 2 …

… -vascular diseases (nephropathy, retinopathy and neuropathy) … of choice for detecting common
genetic variants associated with … of TCF7L2 variants to T2D predisposition and identified …

… 2,3,4,5,6,7,8,9,10,11,12,13 . The identities of the variants and genes mediating the
susceptibility effects at most of these signals have yet to be established, and the known variants …

… studies in an attempt to identify regions conferring this increased susceptibility to … variants
in a known IgA nephropathy (IgAN) gene, complement factor H (CFH), modulated susceptibility …

… in diabetes mellitus type 2 patients with DKD are not associated with the risk for ESKD of a
… genetic variant is small. Previous studies have shown the capability of GRS to measure the …

… genetic predisposition to diabetic nephropathy: only a subset of individuals with type 1 or
type 2 diabetes will develop diabetic nephropathy … common variants in the HMGA2 gene …

… with classes of genetic variation other than common single … variants associated with T2D
susceptibility and β-cell dysfunction, but only maternally-inherited alleles confer increased …

… of genetic predisposition. For example, the heritability for … patients and the genetic variants
of diabetic nephropathy in T2DM … improves kidney outcomes in patients with type 2 diabetes. …

… patients have a positive family history of T1D [6]. However, increased susceptibility to T1D
… as haplotypes facilitated the cataloging of common variants (HAPMAP, 1000 genomes) and …

… prone to other conditions such as heart disease, stroke, hypertension, nephropathy, … implicitly
convey that the India-specific susceptible genetic variants need to be explored extensively. …