… and GFPT2 gene polymorphisms with diabetic nephropathy … Moreover, HMGA2 and
BCL2 genes were also identified as … for type 2 diabetes susceptibility genes in Utah Caucasians. …

… T2D genetic risk information affects behavior is by increasing … ; also vulnerability, likelihood
or susceptibility), which in turn … definition of genetic pathways, novel variants and modeling …

… more variants within the candidate gene are tested; the variants … with increased susceptibility
to Type 2 diabetes mellitus. … activity in diabetes mellitus and diabetic nephropathy. …

… Binding of HMGA2 to the T risk allele was confirmed in EMSA and supershift EMSA in … -
and thus influences lipid metabolism and systemic insulin sensitivity [34]. The non-risk allele of …

… ) gene is a susceptibility gene for schizophrenia. More than 50 splice variants in the DISC1
gene … (CDKAL1) gene have been associated with the risk of type 2 diabetes (T2D). A deficit of …

… by antagonizing Let-7 and increased HMGA2-mediated EMT81. In … nephropathy compared
with patients without diabetic … strong associations with susceptibility to pancreatic cancer105. …

… variants of the ABCC8-KCNJ11wild-type haplotype carriers have shown increased sensitivity
… On the contrary, the rs2237895 variant has been shown to increase repaglinide sensitivity […

… gene approach, the carnosinase genes (CNDP1 and CNDP2) were evaluated for their role
in diabetic nephropathy susceptibility … Variants in the carnosinase genes appear to contribute …

… in diabetes mellitus type 2 patients with DKD are not associated with the risk for ESKD of a
… genetic variant is small. Previous studies have shown the capability of GRS to measure the …

… causal alleles are common, rare, or both (HMGA2, IGF2BP2). … (causing blindness, kidney
disease, nervous system damage, … sensitivity of results to bottleneck size, exponential growth …