The role of spinal serotonin receptor and alpha adrenoceptor on the antiallodynic effects induced by intrathecal milnacipran in chronic constriction injury rats

T Nakamura, T Ikeda, R Takeda, K Igawa… - European Journal of …, 2014 - Elsevier
involved in the antiallodynic and antinociceptive effects of SNRIs in rodent models with
neuropathic pain; however, the involvement … When antinociceptive effects were compared in each …

Pharmacological screening of a new alpha-2 adrenergic receptor agonist, mafedine, in zebrafish

YI Sysoev, DA Meshalkina, DV Petrov, SV Okovityi… - Neuroscience …, 2019 - Elsevier
… also mediate antinociceptive and hypothermic effects of some … clonidine, dexmedetomidine,
tizanidine and other agents [12]. … Compared to clonidine, mafedine has slower and more …

Intrathecal Clonidine as Spinal Anaesthesia Adjuvant—Is there a Magical Dose?

VM Whizar-Lugo, JC Flores-Carrillo… - Topics in Spinal …, 2014 - books.google.com
… intrathecally, the resulting antinociception is greater than … receptor investi‐gated the role of
the alpha2A receptor in … authors compared clonidine 30 µg, sufentanyl 10 µg, clonidine 15µg …

[HTML][HTML] Acupoint stimulation with diluted bee venom (apipuncture) potentiates the analgesic effect of intrathecal clonidine in the rodent formalin test and in a …

SY Yoon, DH Roh, YB Kwon, HW Kim, HS Seo… - The Journal of …, 2009 - Elsevier
… for mice and rats in the present study to investigate the role of … clonidine significantly decreased
motor function compared … enhances the antinociceptive effect of clonidine via a functional …

Clonidine in neuropsychiatric disorders: a review

R Sandyk, MA Gillman, RP Iacono… - International journal of …, 1987 - Taylor & Francis
effects could be due to species differences, other unforeseen … to the antinociceptive effects
of clonidine (Paalzow, 1978; … for involvement in the postsynaptic effects of clonidine. Alpha-…

Dexmedetomidine induces conditioned place preference in rats: Involvement of opioid receptors

T Uskur, MA Barlas, AG Akkan, A Shahzadi… - Behavioural Brain …, 2016 - Elsevier
… did not observe any significant difference between DEX (5–… of phenylephrine and clonidine
decreased the expression of … these results suggest that alpha-adrenoceptor mechanism(s) …

The synergistic interaction between rilmenidine and paracetamol in the writhing test in mice

M Soukupova, T Doležal, M Kršiak - Naunyn-Schmiedeberg's archives of …, 2009 - Springer
… Results describing the effect of rilmenidine in comparison with … On the other hand, the
antinociceptive activity of clonidine, the … receptor agonists such as tizanidine, fadolmidine, …

Significance of the imidazoline receptors in toxicology

JA Lowry, JT Brown - Clinical Toxicology, 2014 - Taylor & Francis
… are involved in the hypotensive activity of clonidine and … ligands may have substantial
antinociceptive activity and work … effects of I-1 agonists to a higher degree compared with AA-2 …

Effects of clonidine on a C-fibre reflex in the rat

M Gozariu, D Bustamante, D Le Bars… - European journal of …, 1996 - Elsevier
… confirming the role of central cr,-adrenoceptors in our experi… , A comparison of clonidine
with morphine for antinociceptive … , 1986, Alpha-adrenoceptormediated antinociception and …

[PDF][PDF] PREMATURE EJACULATION–POTENTIAL ROLE OF α2-ADRENOCEPTOR AGONISTS FOR SYMPTOMATIC TREATMENT

J Lehtimäki - utupub.fi
… The locomotor activity of the mice was assessed in a … activity at a dose of 30 µg in both motor
activity measurement sessions. For comparison, clonidine decreased the motor activity at all …