The mirn23a microRNA cluster antagonizes B cell development
JL Kurkewich, E Bikorimana, T Nguyen… - Journal of Leucocyte …, 2016 - academic.oup.com
… target genes of mirn23a for cell-fate decisions were expressed in uncommitted progenitors.
As the A20 in vitro model is a more differentiated cell line, we wanted to complement this with …
As the A20 in vitro model is a more differentiated cell line, we wanted to complement this with …
CTCF: A Crucial Regulator of Gene Expression in Lymphocytes
C Ribeiro de Almeida - 2010 - repub.eur.nl
… Commitment to the B-lymphoid lineage (pro-B cells) depends … of three hypervariable
complementary determining regions (… control of gene expression during T helper differentiation is …
complementary determining regions (… control of gene expression during T helper differentiation is …
Lineage specification and plasticity in CD19− early B cell precursors
LL Rumfelt, Y Zhou, BM Rowley, SA Shinton… - The Journal of …, 2006 - rupress.org
… differentiation of most early hematopoietic cells (30) and, under these conditions, both myeloid
and B lymphoid … 647 and hybridized with the complementary labeled reference RNA (dye-…
and B lymphoid … 647 and hybridized with the complementary labeled reference RNA (dye-…
[HTML][HTML] B lymphocytes in autoimmunity
JH Izquierdo, CA Cañas, GJ Tobón - Autoimmunity: From Bench to …, 2013 - ncbi.nlm.nih.gov
… is a regulation mechanism of B cell activation and differentiation (… B-lymphoid-specific genes.
Therefore, Pax5 controls … the elongation of the Third Complementarity Determining Region (…
Therefore, Pax5 controls … the elongation of the Third Complementarity Determining Region (…
[PDF][PDF] Lin28b regulation of early-life B lymphopoiesis. A model system to study how self-reactive B cells develop in early life.
H Åkerstrand - 2023 - portal.research.lu.se
… that exerts post-transcriptional gene regulation. The exact LIN28B mechanism in B cell …
To identify the underlying mechanism, we explored the LIN28B mRNA interactome in B cell …
To identify the underlying mechanism, we explored the LIN28B mRNA interactome in B cell …
Signaling networks in B cell development and related therapeutic strategies
A Ren, J Sun, W Yin, LS Westerberg… - Journal of Leukocyte …, 2022 - academic.oup.com
… in the BM and they complement each other on many levels like … epigenetic regulator,
promoting B-lymphoid-specific genes … Apart from initial differentiation, genes regulated by Pax5 …
promoting B-lymphoid-specific genes … Apart from initial differentiation, genes regulated by Pax5 …
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5
JMR Pongubala, DL Northrup, DW Lancki… - Nature …, 2008 - nature.com
… We pursued a complementary gain-of-function approach to … We analyzed cultures for their
development of B lymphoid (… with control GFP or EBF-GFP retrovirus to differentiate for 5 d in …
development of B lymphoid (… with control GFP or EBF-GFP retrovirus to differentiate for 5 d in …
[HTML][HTML] MYC's fine line between B cell development and malignancy
O de Barrios, A Meler, M Parra - Cells, 2020 - mdpi.com
… The inhibition of erythroid differentiation was the first evidence of MYC activity in vitro, …
a complementary function but also is essential for ensuring leukemic transformation [43,45]. …
a complementary function but also is essential for ensuring leukemic transformation [43,45]. …
[HTML][HTML] Differential programming of B cells in AID deficient mice
MA Hogenbirk, MR Heideman, A Velds… - PloS one, 2013 - journals.plos.org
… In some B lymphoid cancers … in gene regulation of non-B cell systems [13], [14], [15]. To
explore the possibility that AID alters transcription in B cells to control B cell differentiation we …
explore the possibility that AID alters transcription in B cells to control B cell differentiation we …
Innate B cells: the archetype of protective immune cells
A Grasseau, M Boudigou, L Le Pottier, N Chriti… - Clinical reviews in …, 2020 - Springer
… a complement-dependent mechanism. When bound, IgM is an early recruiter of C1q that
activates the classical complement … plasmablast differentiation and acquired regulatory function …
activates the classical complement … plasmablast differentiation and acquired regulatory function …