… a permissive gene transcription. Epigenetic mechanisms also regulate the differentiation of
… , and tumor cells) by activating complement and/or interacting with lytic cells. During B cell …

… level in the B lymphoid lineage from the earliest detectable precursor to the mature B cell
stage. Pax5 expression was, however, not detected in terminally differentiated plasma cells …

… progenitors and B lymphoid progenitors (… complement the Batf deficiency during ILC
differentiation. Considerable increases in ILC differentiation were detected after the Nfil3 or Id2 gene …

Since the dawn of multicellular life, cells have diversified through the differentiation of …
differentiation. In this thesis, I challenged this view by investigating whether cell-type differentiation …

… and helps it to find its complementary sequence, which is … differentiation was reported
in Science in 2004. The study found that MiR-181 was preferentially expressed in the B-lymphoid …

The zinc-finger transcription factor GATA-3 has received much attention as a master regulator
of T helper 2 (Th2) cell differentiation, during which it controls interleukin-4 (IL-4), IL-5, and …

… at least partial sequences complementary to their sequence (… miRNAs in normal B-cell
differentiation and function, as the … was shown to compromise B-lymphoid and erythroid lineage …

… gene expression, we wanted to establish a model system that allowed for a reasonable
approximation of the gene expression profile during B lymphoid differentiation. … complementary to …

… incidence of other B-lymphoid neoplasms was observed (64). … cell differentiation genes,
particularly Blimp1 and Irf4 (99, 100). … and complementary in vivo studies (80, 108). The …

… In an attempt to override the B-lymphoid differentiation block, we next expressed E2A-PBX1 …
and survival complements Cdkn2a deletion in protecting B-lymphoid progenitors from E2A-…