… CD180, and this effect was phenocopied by PIM inhibitors. PIM… amounts of CD40L, since
CD40 further up-regulates PIM-1 … HEL cells with constitutively high, PIM-independent pBAD …

… 1 (LMP1) of the Epstein Barr virus (EBV) mimics constitutive … This is in line with additional in
vivo and in vitro data … factor FoxP3102,103 is mainly phenocopied by deficiencies in CD25, IL…

… Loss of Ampk in WT MEFs phenocopies loss of Lkb1 by … T2 and T3 cells, can respond to
signals from T cells in vivo. … by exogenous expression of a constitutively active Ampk construct […

… prostate cancer suggesting that epigenetic mechanisms may contribute to constitutive NF- …
often adopt mixed M1/M2 phenotypes in vivo and can be repolarized with changing …

… People with mutations in vHL—and therefore constitutively elevated HIF levels—have …
Epstein-Barr virus (EBV) oncoprotein latent membrane protein 1 (LMP1) activates HIF-1α by …

… immunoglobulin class switching to occur in vivo [22]. Interestingly, … Epstein Barr Virus protein
LMP1 acts as a constitutively active CD40 isoform that helps drive oncogenic transformation …

… All in vivo experiments were … the CD40 and lymphotoxin-β receptors by B-cell-activating
factor of the TNF family (BAFF), LPS and latent membrane protein-1 (LMP1) of Epstein–Barr virus…

… receptors with erbB-2 oncogene as well as in vivo data from ob/… the Epstein-Barr virus
transforming protein, LMP1 signaling … The defects recorded in Akt1/Akt2 DKO mice phenocopy IGF-…

… and rapidly eliminate infected or transformed cells. Although T¬… 115 Figure 3.18 In vivo
kinetics of IFNγ and PD-1 expression … virus (HIV) (23, 24), primary Epstein-Barr virus (EBV) (25), …

… For the purpose of the current body of work, all array data were transformed using a
logarithm to the base e (Kolmogorow-Smirnov test of normality with Lilliefors correction p <0.00'1). …