[PDF][PDF] MOLECULAR MODELLING OF THE CANNABINOID RECEPTORS: STRUCTURE BASED DESIGN, SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF …
JLOOS EE - 2015 - core.ac.uk
… that CB1 receptors located in the brainstem region control the … Multiple sclerosis (MS) is
an autoimmune, inflammatory … receptor, and the conformations ranked in order to provide a …
an autoimmune, inflammatory … receptor, and the conformations ranked in order to provide a …
Advances in diagnostics and treatment of neurotoxicity after sports-related injuries
TA Gennarelli, SA Dambinova, JD Weissman - 2017 - books.rsc.org
… autoimmune reaction with Ab formation leading to the risk of brain … to nanoparticles or
inserted into liposomes. To evade toxic side … through reversible inhibition of glutamate receptors, …
inserted into liposomes. To evade toxic side … through reversible inhibition of glutamate receptors, …
Carcinoid syndrome: preclinical models and future therapeutic strategies
… (VMAT1), metabotropic glutamate receptor 4, b1-adrenergic receptor, … inflammatory syndrome
in a patient with an atypical multisystem illness with CS as well as atopic and autoimmune …
in a patient with an atypical multisystem illness with CS as well as atopic and autoimmune …
The role of the sigma subunit of Adaptor Protein-2, AP2σ2, in the regulation of calcium homeostasis
A Rogers - 2016 - ora.ox.ac.uk
… Allosteric modulators of … Positive allosteric modulators of the CaSR comprising NPS R-568,
cinacalcet, AC- 265347, glutathione, and L-phenylalanine. (B) Negative allosteric modulators …
cinacalcet, AC- 265347, glutathione, and L-phenylalanine. (B) Negative allosteric modulators …
Designing Immunotherapies for Cancer Treatment
Z Wan - 2021 - search.proquest.com
… a novel role of the metabotropic glutamate receptor-4 (GRM4) in … in immune modulation
was first described in an autoimmune … ), a Grm4-positive allosteric modulator, led to increased …
was first described in an autoimmune … ), a Grm4-positive allosteric modulator, led to increased …
XIth International Symposium on Cholinergic Mechanisms-Function and Dysfunction & 2nd Misrahi Symposium on Neurobiology
I Silman… - 2002 - apps.dtic.mil
… Send comments regarding this burden estimate or any other aspect of this collection of
Information, including suggestions for reducing this burden to Washington Headquarters Services…
Information, including suggestions for reducing this burden to Washington Headquarters Services…
[PDF][PDF] β-Amyloid Therapeutic Strategies for Alzheimer's Disease
F Speroni - 2005 - researchgate.net
… (NMDA) receptor complex is a subtype of glutamate receptor … , controlled studies aimed at
reducing inflammation in the brain … is an allosteric modulation of -secretase activity (267-269), …
reducing inflammation in the brain … is an allosteric modulation of -secretase activity (267-269), …
The pathophysiology and therapeutic potential of purinergic signalling
G Burnstock - Purinergic Signalling, 2017 - Springer
… increased in septic monocytes when compared with a control … new agonists or positive
allosteric modulators able to boost … receptors represent good targets to suppress inflammatory …
allosteric modulators able to boost … receptors represent good targets to suppress inflammatory …
Structure Elucidation, Signaling Mechanism and Structure-Based Lead Design of the Human Cannabinoid Receptor 2 (CB2)
C Xing - 2020 - search.proquest.com
… modulators give us a better chance to design CB1 or CB2 selective drugs because most of
the … Although several CB1 and CB2 allosteric modulators have been developed, we are still in …
the … Although several CB1 and CB2 allosteric modulators have been developed, we are still in …
Impact of Juvenile Stress on Hippocampal Synaptic Plasticity and Memory in Adult Rats
R Raghuraman - 2019 - search.proquest.com
… altered levels in pro-inflammatory cytokines that are released … /ERK kinase Metabotropic
glutamate receptor Mammalian … (a positive allosteric modulator of AMPA receptors) resulted …
glutamate receptor Mammalian … (a positive allosteric modulator of AMPA receptors) resulted …