… specific therapy by organoid culture using tumour-derived organoids. c Future applications
of organoids may involve a more direct role in treatment, such as using organoids to generate …

… the current research. Researchers are engrossed on the discovery and refinement of techniques
in growing different types of organoids and … While the general premise is that organoid …

… The main models used include tumour-derived two-dimensional (2D) cell culture, PDXs
and more recently three-dimensional (3D) ‘organoid’ culture. Each technique has benefits, as …

… cancer include spheroids, patient-derived organoids, microfluidic systems, patient-… present
a review of available 3D modelling systems in endometrial cancers, highlighting their current …

… reverse the polarity (apical-out polarity) of cystic organoids grown in ECM 37 or to establish
patient-derived glioblastoma organoids 38 . In this instance, glioblastoma samples were cut …

… Interestingly, BCN057 did not have a radiomitigative effect in tumour-derived organoids
with these findings again mimicking in vivo findings. The same group also investigated the …

… The receptor status of the parental tumour was lost in only a small number of organoid
cases, yet this highlights the need to adequately characterize tumour-derived organoids before …

… Fortunately, the emergence of patient-derived organoid (PDOs) culture has enabled the ex
… (GI) tumors, herein we present the state-of-the-art and the current methodology of PDOs. We …

… oxygen supply to the cells and preserves the organoids for 30–60 days (Figure 1a). ALI
culture has enabled non-tumour and tumour-derived tissue samples to be cultured with native …

… Therefore, the aim of the current study is to establish and optimise an in vitro 3D co-…
organoids with PBMCs and purified T cells and to study growth inhibition and induction of organoid …