… N-methyl-D-aspartate receptor (NMDAR)-mediated … D-cycloserine, a partial agonist at the
glycine site of NMDAR, was reported in some clinical studies to activate the NMDAR in brains …

… receptor with glycine and cycloserine (D-cycloserine). Recently, … to accumulate in the brains
of individuals with Alzheimer’s … NMDA receptor activation and neuronal injury in brain areas …

… partial agonist D-cycloserine gained interest as a nootropic agent … In humans with Alzheimer’s
disease, D-cycloserine … the N-methyl-D-aspartate receptor–ionophore complex in human …

… Alzheimer patients, D-cycloserine facilitates activation of the NMDA receptor-ionophore
complex (… activation ofthe N-methyl-o-aspartate receptor-ionophore complex in Alzheimer brain. …

… of a putative partial agonist, D-cycloserine, at the glycine modulatory site of the N-methyl-D-aspartate
receptor-ionophore complex (… prepared from Alzheimer's brains, D-cycloserine was …

… , d-cycloserine, as therapeutic agents for ataxia in a murine model. Both compounds are known
to stereospecific modulate N-methyl-d-aspartate … disturbance in Alzheimer's patients 2, 27…

… formulate a complex glutamatergic network in the brain that … The iGluRs include N-methyl-D-aspartate
(NMDA), α-amino-3… the NMDA ion channel pore and facilitate the passage of Ca 2 …

… N-methyl-D-aspartate receptor augmentation of psychotropic drug treatment in these two
individuals. Glycine was used in the first clinical trial, and D-cycloserine … levels of brain glycine …

… reported that the glutamatergic N-methyl-d-aspartate (NMDA) … respond differently to treatment
with d-cycloserine (DCS), a … and is required for receptor activation by glutamate [16], [22]. …

… N-methyl-d-aspartate (NMDA) glutamate receptor, such as phencyclidine and ketamine,
produce cognitive … abnormalities of glutamate receptors in brains of patients with schizophrenia, …