[HTML][HTML] DNA methylation, its mediators and genome integrity

H Meng, Y Cao, J Qin, X Song, Q Zhang… - … journal of biological …, 2015 - ncbi.nlm.nih.gov
… In this review, we introduce various forms of DNA methylation in terms of distributions and
… of mediators of DNA methylation and demethylation, including DNA methyltransferases (…

Preserving genome integrity and function: the DNA damage response and histone modifications

JJ Kim, SY Lee, KM Miller - Critical reviews in biochemistry and …, 2019 - Taylor & Francis
… , processing, and repairing damaged DNA to ensure the integrity of genetic information and
… relate to DNA damage responses (DDRs) and their involvement in genome maintenance, …

Oxidative stress and alterations in DNA methylation: two sides of the same coin in reproduction

YJR Menezo, E Silvestris, B Dale, K Elder - Reproductive biomedicine …, 2016 - Elsevier
DNA methylation and epigenetic errors. Age has a negative effect on oxidative stress and
DNA methylation, … transmitting epigenetic disorders to their offspring. Environmental endocrine …

Epigenetic regulation of genomic integrity

AK Deem, X Li, JK Tyler - Chromosoma, 2012 - Springer
… One protein that is directly recruited by γH2AX to repair foci is mediator of DNA damage
checkpoint protein 1 (MDC1). MDC1 binds to γH2AX via its BRCT domain and accumulation of …

DNA methylation and regulation of gene expression: Guardian of our health

GA Dhar, S Saha, P Mitra, R Nag Chaudhuri - The Nucleus, 2021 - Springer
… During developmental phases, the DNA methylation pattern in the genome … novo DNA
methylation and demethylation. Resultantly, differentiated cells inherit a unique DNA methylation

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

J Lukas, C Lukas, J Bartek - Nature cell biology, 2011 - nature.com
… the genome against destabilizing effects posed by tiny DNA lesions… DNA damage are not
simply the accumulation of 'nuclear foci' but are mechanisms required to guard genome integrity

Enhancer DNA methylation: implications for gene regulation

A Angeloni, O Bogdanovic - Essays in biochemistry, 2019 - portlandpress.com
… explores DNA methylation in cancer, the role of DNA methylationDNA demethylation, 5mC
is diluted following several rounds of DNA replication due to the absence of DNA methylation

Epigenetics and genome stability

JX Feng, NC Riddle - Mammalian Genome, 2020 - Springer
… for ensuring genome integrity in the face of the continuous challenges that induce DNA
damage… We discuss histone variants and modifications, DNA methylation, and non-coding RNAs …

Role of oxidative stress, genome damage and DNA methylation as determinants of pathological conditions in the newborn: an overview from conception to early …

R Scarpato, S Testi, V Colosimo, CG Crespo… - … Research/Reviews in …, 2020 - Elsevier
… tube defects, alter genome integrity of the newborns or induce DNA hypomethylation, thus
… capacity in the newborns who expressed a different pattern of inflammation mediators [70]. …

Sirtuin‐dependent epigenetic regulation in the maintenance of genome integrity

L Bosch‐Presegué, A Vaquero - The FEBS journal, 2015 - Wiley Online Library
… , DNA repair, cell fate and the cell cycle. This substrate diversity reflects the importance of
sirtuins as mediators … it also facilitates DNA methylation by recruiting DNA methyltransferases […