… In recent years, the epigenetic therapies used in cancer have made significant progress,
mainly due to the rapid development of genome-wide high-throughput sequencing technology. …

… Epigenetic treatment may therefore benefit cancer patients … and a combinatory treatment
with other current therapy. In this … DNA methylation is the most extensively studied epigenetic …

… DNA methyltransferase inhibitors have been approved as first-generation epigenetic inhibitors
for cancer therapy… knowing the status of DNA methylation as with DNA epigenetic mark, 5-…

… examined for their anti-cancer or therapeutic effects on neurological diseases. Three main
epigenetic treatments are in a reliable consideration: DNMT and HDAC inhibitors and miRNA-…

… in TNBC cells partially by epigenetically reprograming EMT. Our findings strongly suggest
that TNBC is sensitive to epigenetic therapies. Therefore, we propose a new strategy to treat …

… Epigenetic therapies using the inhibitors of these enzymes have anti-tumorigenic effects on
… on DNA methylation inhibitors and histone deacetylation inhibitors evaluating their potential …

… to further advance epigenetic therapies. DNA methylation is an epigenetic change that results
… , a process mediated by DNA methyltransferase enzymes (DNMTs). To date, three types of …

… epigenetic therapy which has especially focused on DNMT and HDAC inhibitors as enlightened
epigenetic mechanisms in cancer … , is a small molecule of DNA methylation inhibitor. SGI-…

… for future epigenetic therapies will be to develop inhibitors with … achieved with DNA
methylation inhibitors, there is still … available DNA methylation inhibitors block DNA methylation …

… In this review, we discuss both established and emerging epigenetic therapies in … Alteration
in DNA methylation status is a characteristic epigenetic change in many cancers including …