… Epigenetic therapy in hematological malignancies is the most … an epigenetic drug by reducing
DNA methylation rather than direct cytotoxic agent. Both have been approved for treatment …

… epigenetic modifications in cancer. Various post translational modifications of histone proteins
together with DNA methylation constitute an ‘epigenetic … applying epigenetic therapies in …

… molecule inhibitors of the key epigenetic enzymes (epigenetic … epigenetic therapeutic
approaches [9]. Consequently, the discovery of small molecule inhibitors against these epigenetic …

… , and its deregulation is linked, for example, to cancer, … Key epigenetic mechanisms
are DNA methylation, histone … DNA methylation is deposited and maintained by DNA-…

… epigenetic therapy, often in combination with other therapies, will become a potent tool for
cancer … O6-methylguanine-DNA methyltransferase, and epigenetic therapy with DNMTi in this …

… epigenetic abnormalities in ovarian cancer, discuss key scientific advances using epigenetic
therapies in preclinical ovarian cancer models… The epigenetic modification DNA methylation …

… epigenetic therapies provide a clinical benefit through disrupting DNA methyltransferases or
… However, the emergence of next-generation epigenetic therapies provides an opportunity to …

… DNA methyltransferase inhibitors as an emerging anticancer strategy. This review covers
potential epigenetic … Combining epigenetic therapies has shown both additive and synergistic …

… Despite these benefits, epigenetic therapy as a single therapy or in … DNA methyltransferase
inhibitors (DNMTi) are used as an anticancer therapy and clarify DNA methylation …

… epigenetic agents were DNA methyltransferase inhibitors; these were followed by histone
deacetylase inhibitors (… onstrated that epigenetic therapy with a DNMT inhibitor induced such …