… of experimental animal models of IgA nephropathy can be … to have faulty IgG receptor
function, a similar abnormality of IgA … nephritogenic IgA2 anti-IgA fragment immune complexes. …

… ], and kidney function itself, promote the progression of IgAN. … generated by galactose-deficient
IgA (Gd-IgA1) and … experimentally using gliadin, which is present in grains such …

… used in experimental models of IgA nephropathy discussed in the … : Defective oral tolerance
promotes nephritogenesis in experimental IgA nephropathq induced by oral immunization. f …

… This hypothesis was partially supported by an experiment … IgA nephropathy following repeated
oral exposure to either bovine … of nephritogenic effector T cells and interstitial nephritis in …

… aspects through the use of experimental models. Small-animal … The nephritogenic potential
of hypogalactosylated IgA was … defect of IgA is not the sole cause and is not a prerequisite for …

… Such binding promotes or augments … , antigen/immunoglobulin A aggregates alter mesangial
cell eicosanoid synthesis. In vivo, large-lattice cross-linking by particulate antigen promotes …

… to induce an increase of serum BAFF and galactose deficient-… All experiments were performed
in accordance with French … mice (22), confirming that nephritogenic IgA is modulated by a …

… Experimental evidence for this is provided by a murine mode… are poorly understood,
although likely to involve defects in … process following a primary nephritogenic stimulus, to a …

… IgA nephropathy (IgAN) is characterized by deposition in the … These mesangial codeposits
may participate in the nephritogenesis … Experiments were performed with IgA produced by the …

… IgG, and IgM was not induced in IgA-deficient mice. These results demonstrate … enhances
the production of glycosylated IgA. In IgA nephropathy, it was clarified that the deposition of IgA …