Correcting autoimmune anomalies in autoimmune disorders by immunological means, employing the modified vaccination technique

AZ Barabas, CD Cole, AD Barabas, RM Graeff… - Autoimmunity …, 2009 - Elsevier
… a new vaccination technique in experimental animals that … ag, promoting slow or rapid
removal of cell debris; defective or … the native nephritogenic ag and rat anti-nephritogenic ag IgM …

Studies of the pathogenesis of IgA nephropathy and Henoch-Schönlein purpura, with special reference to Streptococcus pyogenes infections and complement

R Schmitt - 2012 - portal.research.lu.se
… II-deficient mice caused mesangial … experiments have shown that IL-6 induces mesangial
cell proliferation and extracellular matrix expansion in renal glomeruli215. The nephritogenic

The influence and role of microbial factors in autoimmune kidney diseases: a systematic review

A Kronbichler, J Kerschbaum… - Journal of Immunology …, 2015 - Wiley Online Library
… of IgA vasculitis and IgA nephropathyexperimental setting investigating the role of outer
membrane antigen components of Haemophilus parainfluenzae indicated a direct nephritogenic

Optimizing the translational value of animal models of glomerulonephritis: insights from recent murine prototypes

MH Foster - American Journal of Physiology-Renal …, 2016 - journals.physiology.org
… fresh insight into mediators of IgA nephropathy and origins of … , to determine the origin of
nephritogenic autoimmunity, and to … by classic experiments in which GN was induced in squirrel …

The molecular phenotype of endocapillary proliferation: novel therapeutic targets for IgA nephropathy

JB Hodgin, CC Berthier, R John, E Grone, S Porubsky… - PLoS …, 2014 - journals.plos.org
… With this approach we compared our gene signatures to expression profiles in experimental
in vitro models of cellular responses to a panel of bioactive molecules [27]. Using this …

T cells in glomerulonephritis

PG Tipping, SR Holdsworth - Springer seminars in immunopathology, 2003 - Springer
nephritogenic immune responses in experimental models … , it is not surprising that MHC
II-deficient mice do not develop an … human GN including lupus nephritis [125], IgA nephritis [126] …

The molecular basis of IgA nephropathy

I Stephen, H Hsu, J Feehally - … Genetic Basis of Renal Disease E …, 2007 - books.google.com
… evidence on its control comes from experimental animals. … with IgAN, arguing against defective
clearance by this route, … the IgA system, resulting in production of IgA with nephritogenic

[HTML][HTML] Inflammation and Inflammatory Mediators in Kidney Disease: Optimizing the translational value of animal models of glomerulonephritis: insights from recent …

MH Foster - American Journal of Physiology-Renal Physiology, 2016 - ncbi.nlm.nih.gov
… fresh insight into mediators of IgA nephropathy and origins of … , to determine the origin of
nephritogenic autoimmunity, and to … by classic experiments in which GN was induced in squirrel …

Mesangial deposition can strongly involve innate-like IgA molecules lacking affinity maturation

B Wehbi, C Oblet, F Boyer, A Huard… - Journal of the …, 2019 - journals.lww.com
IgA nephropathy (IgAN) is characterized by IgA mesangial … Among several existing IgAN
experimental models, none … This results in the formation of bulky nephritogenic immune …

[图书][B] Interleukins 4 and 5 alter IgA glycosylation: Ramifications for the pathogenesis of IgA nephropathy

SC Rao - 1996 - search.proquest.com
… in vitro experiments, we generated antigen-specific IgA, by … structurally abnormal IgA that
promotes IgA mesangial deposition … These studies suggest that defective oral tolerance may be …