… of mouse germinal vesicle stage–oocytes and their subsequent in vitro maturation improves meiotic spindle configuration and mitochondrial distribution in metaphase II oocytes

AR Moawad, B Xu, SL Tan, T Taketo - Human reproduction, 2014 - academic.oup.com
ATP levels in MII oocytes may have been increased by LC supplementation. Our results,
however, showed that ATP levels in MII oocytesoxidative stress that could occur during oocyte

[HTML][HTML] Oocyte mitochondria: role on fertility and disease transmission

MR Chiaratti, BM Garcia, KF Carvalho… - Animal …, 2018 - ncbi.nlm.nih.gov
… of protecting mitochondria from oxidative damage that result in … meiotic spindle (on the
ovulated oocyte), provides energy at specific … As a result, MFN1 deficiency has a larger impact on …

[HTML][HTML] IGF2 improves the developmental competency and meiotic structure of oocytes from aged mice

T Muhammad, Y Wan, Q Sha, J Wang, T Huang… - Aging (albany …, 2021 - ncbi.nlm.nih.gov
… production and the incidence of spindle/chromosome defects. … functional activity by reducing
oxidative stress, as well as by … deficits in non-aged female infertility patients (eg, oocytes

Oxidative phosphorylation-linked respiration in individual bovine oocytes

S Sugimura, S Matoba, Y Hashiyada… - … of Reproduction and …, 2012 - jstage.jst.go.jp
… This result correlates with microarray data in mouse oocytes … of protection from oxidative
damage during in vitro maturation. … In the present study, we confirmed impaired ATP-linked …

[HTML][HTML] Mitochondria: the panacea to improve oocyte quality?

L Qi, X Chen, J Wang, B Lv, J Zhang… - Annals of Translational …, 2019 - ncbi.nlm.nih.gov
… of meiotic spindles and the maintenance of the metaphase II (MII) … development,
mitochondria-derived energy gradually come to … in protecting oocyte from oxidative damage and …

The spatio-temporal dynamics of mitochondrial membrane potential during oocyte maturation

U Al-Zubaidi, J Liu, O Cinar, RL Robker… - Molecular Human …, 2019 - academic.oup.com
… and oxidative stress are all associated with defects in oocyte … cristae structure and reduced
ATP production (Ottosen et al., … portion of the spindle-containing hemisphere with that at the …

Melatonin prevents oocyte deterioration due to cotinine exposure in mice

J Cheng, P Mi, Y Li, Y Lu, F Sun - Biology of Reproduction, 2022 - academic.oup.com
… It has been suggested that smoking impairs oocyte function and … with ATP supply, oxidative
stress, and apoptosis [24]. … that oxidative stress in mouse oocytes increases meiotic spindle

[PDF][PDF] Mitochondrial heterogeneity and sorting in mammalian oocytes and pre-implantation embryos

J Liu - 2021 - scholar.archive.org
… Once the spindle reaches the cortical domain of the oocyte, … affected, where old mouse
oocytes showed reduced ATP level … may be one of the reasons why aging affects oocyte quality. …

[HTML][HTML] High fat diet induced developmental defects in the mouse: oocyte meiotic aneuploidy and fetal growth retardation/brain defects

KM Luzzo, Q Wang, SH Purcell, M Chi, PT Jimenez… - PloS one, 2012 - journals.plos.org
… We therefore evaluated ovulated MII oocytes for spindle and … It is thus tempting to speculate
that the deficits in … , such as the level of oxidative stress, which could be more severe in this …

Oocyte senescence: a firm link to age-related female subfertility

C Tatone - Gynecological Endocrinology, 2008 - Taylor & Francis
… negatively affects the storage of oocyteoxidative stress decreased mitochondria-derived
ATP, a condition which was, in turn, responsible for a disassembly of mouse MII oocyte spindles