[HTML][HTML] Advanced maternal age alters expression of maternal effect genes that are essential for human oocyte quality

JJ Zhang, X Liu, L Chen, S Zhang, X Zhang… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
… associated with spindle assembly checkpoints in older oocytes, … The function of mitochondria
affects the quality of oocytes … , oxidative stress, titin binding and immune function, while

[HTML][HTML] Deciphering reproductive aging in women using a NOD/SCID mouse model for distinct physiological ovarian phenotypes

M Marchante, N Ramirez-Martin, A Buigues… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
… include those with the BRCA2 receptor deficiency [14], follicle-… oxidative damage that disrupts
folliculogenesis and oocyte meiosis [55, 56] and contributes to the accumulation of spindle

Effect of vitrification on meiotic maturation, mitochondrial distribution and glutathione synthesis in immature silver fox cumulus oocyte complexes

X Cao, J Li, H Xue, S Wang, W Zhao, Z Du, Y Yang… - Theriogenology, 2017 - Elsevier
damage to mitochondria and the GSH synthesis deficiencyaffects mitochondrial distribution
and GSH synthesis duringspindle against oxidative damage and maintaining spindle

Changes in mitochondrial function in porcine vitrified MII-stage oocytes and their impacts on apoptosis and developmental ability

J Dai, C Wu, CW Muneri, Y Niu, S Zhang, R Rui… - Cryobiology, 2015 - Elsevier
… The present study showed that the ATP concentration of porcine vitrified-thawed oocytes
The result of down-regulation of Bcl2 gene in this study was similar to the report in mouse

… of coenzyme Q10 into bovine oocytes improves mitochondrial features and alleviates the effects of summer thermal stress on developmental competence

M Gendelman, Z Roth - Biology of reproduction, 2012 - academic.oup.com
… and therefore impair oocyte developmental competence. … , might impair that chain of events
and cause a decline in ATP … also be a result of oxidative damage prevention. It should be …

Polymerase subunit gamma 2 affects porcine oocyte maturation and subsequent embryonic development

SK Lee, MH Zhao, Z Zheng, JW Kwon, S Liang, SH Kim… - Theriogenology, 2015 - Elsevier
… a drug that limits ATP synthesis, retards mouse oocyte maturation and causes … ATP derived
from mitochondria because of oxidative stress perturbs spindle formation in MII-stage oocytes

[HTML][HTML] Aristolochic acid I exposure decreases oocyte quality

W Li, J Zhang, X Yu, F Meng, J Huang… - Frontiers in Cell and …, 2022 - frontiersin.org
spindles also resulted from reduced ATP production in AAI-exposed … ATP deficiency and
excessive ROS could disturb the … Therefore, AAI exposure may cause oxidative stress in oocytes

FGF2, LIF, and IGF-1 supplementation improves mouse oocyte in vitro maturation via increased glucose metabolism

A Nahar, J Becker, R Pasquariello… - Biology of …, 2024 - academic.oup.com
Deficit of mitochondria-derived ATP impairs mouse oocyteDeficit of mitochondriaderived
ATP during oxidative stress impairs mouse MII oocyte spindles. Cell Res 2006; 16:841–850. 60…

An interplay between epigenetics and translation in oocyte maturation and embryo development: assisted reproduction perspective

M Dvoran, L Nemcova, J Kalous - Biomedicines, 2022 - mdpi.com
… [45,52], significantly impaired the course of meiosis in mouse oocytes, and … deficiency of
mitochondria-derived ATP provoked by oxidative stress induces spindle disruption in MII mouse

Protecting the future: balancing proteostasis for reproduction

AJ Sala, RI Morimoto - Trends in cell biology, 2022 - cell.com
… This occurs through ATP-dependent or -independent cycles of … secondary oocyte arrested
at metaphase II is released during … In mice, HSPA2 is essential for the completion of meiosis I, …